Modulation of noradrenergic neurotransmission by prejunctional auto- and heteroreceptors in the freely moving rat

Robert Paul Coppes

Research output: ThesisThesis fully internal (DIV)

58 Downloads (Pure)

Abstract

Prejunctional receptors modulating noradrenaline release from sympathetic nerves have been studied extensively during the last two decades. Most evidence supporting a modulatory role for these receptors has been obtained from studies using isolated tissues, in situ perfused organs, pithed animals or anaesthetized animals. In this thesis two different models were used to study the in vivo function and capacity of prejunctional auto- and heteroreceptors modulating endogenous noradrenaline overflow in the vasculature of freely moving rats. ... Zie: Summary
Original languageEnglish
QualificationDoctor of Philosophy
Supervisors/Advisors
  • Zaagsma, Johan, Supervisor
Publisher
Print ISBNs90960067507
Publication statusPublished - 1993

Keywords

  • Noradrenaline , Bruine rat, Receptoren , Sympathisch zenuwst
  • neurologie
  • dierfysiologie

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