Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin: A narrative review

Judith E. K. R. Hentzen, Steven J. de Jongh, Patrick H. J. Hemmer, Willemijn Y. van der Plas, Gooitzen M. van Dam, Schelto Kruijff*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

7 Citations (Scopus)
240 Downloads (Pure)

Abstract

Patients with peritoneal carcinomatosis (PC) from colorectal origin may undergo cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) as a curative approach. One major prognostic factor that affects survival is completeness of cytoreduction. Molecular Fluorescence Guided Surgery (MFGS) is a novel intraoperative imaging technique that may improve tumor identification in the future, potentially preventing over- and under-treatment in these patients. This narrative review outlines a chronological overview of MFGS development in patients with PC of colorectal origin.

Original languageEnglish
Pages (from-to)332-343
Number of pages12
JournalJournal of Surgical Oncology
Volume118
Issue number2
DOIs
Publication statusPublished - 1-Aug-2018

Keywords

  • colorectal cancer
  • molecular fluorescence-guided surgery
  • peritoneal carcinomatosis
  • review
  • HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY
  • ENDOTHELIAL GROWTH-FACTOR
  • GLOBAL CANCER STATISTICS
  • SENTINEL LYMPH-NODE
  • INDOCYANINE-GREEN
  • CYTOREDUCTIVE SURGERY
  • PHOTODYNAMIC THERAPY
  • CARCINOEMBRYONIC ANTIGEN
  • PHASE-I
  • SYSTEMIC CHEMOTHERAPY

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