Multicomponent reactions: development, scope, and applications

Ajay Chandgude

Multicomponent reactions: development, scope, and applications

Ajay Chandgude

Drug Design

Research output: Thesis › Thesis fully internal (DIV)

3330 Downloads (Pure)

Abstract

Multi-component reaction (MCR) is a promising synthetic methodology for the rapid and easy access to scaffold with a great diversity and so MCRs find broad applications in pharmaceutical and organic industries. MCRs are considered as ideal reactions due to a wide range of advantages, such as simplicity, high efficiency, green nature, and time efficacy. The finding of new MCRs and their applications to fill chemical space has become an increasingly active area of research.
The research in this thesis is focused on the development of new MCRs and their applications towards generation of biologically important molecules with vast diversity and complexity.

Translated title of the contribution	Multicomponent reacties; Ontwikkeling, Scope en Toepassingen
Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Groningen
Supervisors/Advisors	Dömling, Alex, Supervisor Quax, W. J., Supervisor
Award date	19-Jun-2017
Place of Publication	[Groningen]
Publisher	University of Groningen
Print ISBNs	978-90-367-9931-7
Electronic ISBNs	978-90-367-9930-0
Publication status	Published - 2017

Access to Document

Title and contentsFinal publisher's version, 106 KB
Chapter 1Final publisher's version, 869 KB
Chapter 2Final publisher's version, 840 KB
Chapter 3Final publisher's version, 355 KB
Chapter 4Final publisher's version, 479 KB
Chapter 5Final publisher's version, 499 KB
Chapter 6Final publisher's version, 520 KB
Chapter 7Final publisher's version, 293 KB
Chapter 8Final publisher's version, 367 KB
Chapter 9Final publisher's version, 552 KB
SummaryFinal publisher's version, 153 KB
SamenvattingFinal publisher's version, 182 KB
AcknowledgementsFinal publisher's version, 111 KB
Complete thesisFinal publisher's version, 4.26 MB
PropositionsFinal publisher's version, 136 KB

Cite this

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abstract = "Multi-component reaction (MCR) is a promising synthetic methodology for the rapid and easy access to scaffold with a great diversity and so MCRs find broad applications in pharmaceutical and organic industries. MCRs are considered as ideal reactions due to a wide range of advantages, such as simplicity, high efficiency, green nature, and time efficacy. The finding of new MCRs and their applications to fill chemical space has become an increasingly active area of research. The research in this thesis is focused on the development of new MCRs and their applications towards generation of biologically important molecules with vast diversity and complexity.",

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AB - Multi-component reaction (MCR) is a promising synthetic methodology for the rapid and easy access to scaffold with a great diversity and so MCRs find broad applications in pharmaceutical and organic industries. MCRs are considered as ideal reactions due to a wide range of advantages, such as simplicity, high efficiency, green nature, and time efficacy. The finding of new MCRs and their applications to fill chemical space has become an increasingly active area of research. The research in this thesis is focused on the development of new MCRs and their applications towards generation of biologically important molecules with vast diversity and complexity.

M3 - Thesis fully internal (DIV)

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