Multiway calibration in 3D QSAR: applications to dopamine receptor ligands

Jonas Nilsson

Multiway calibration in 3D QSAR: applications to dopamine receptor ligands

Jonas Nilsson

Faculty of Science and Engineering

Research output: Thesis › Thesis fully internal (DIV)

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Abstract

There are many opinions about how medicinal chemistry should be practiced. The procedure described in this thesis for the design of new drugs comprises several steps including the selection of a lead compound, experimentald esign, syntheseso f new compounds, pharmacological in vitro testing, molecular modeling and multivariate statistical evaluation. Each step has achieved more or less attention but the main emphasis has been put on the multivariate statistical evaluation. ... Zie: Summary

Original language	English
Qualification	Doctor of Philosophy
Publisher	s.n.
Publication status	Published - 1998

Keywords

Multivariate analyse
Proefschriften (vorm)
QSAR
Farmacochemie
44.33

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stelling.pdfFinal publisher's version, 8.33 KB
summary.pdfFinal publisher's version, 15.2 KB
thesis.pdfFinal publisher's version, 1.32 MB

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title = "Multiway calibration in 3D QSAR: applications to dopamine receptor ligands",

abstract = "There are many opinions about how medicinal chemistry should be practiced. The procedure described in this thesis for the design of new drugs comprises several steps including the selection of a lead compound, experimentald esign, syntheseso f new compounds, pharmacological in vitro testing, molecular modeling and multivariate statistical evaluation. Each step has achieved more or less attention but the main emphasis has been put on the multivariate statistical evaluation. ... Zie: Summary",

keywords = "Multivariate analyse, Proefschriften (vorm), QSAR, Farmacochemie, 44.33",

author = "Jonas Nilsson",

note = "date\_submitted:1998 Rights: University of Groningen",

year = "1998",

language = "English",

publisher = "s.n.",

}

TY - BOOK

T1 - Multiway calibration in 3D QSAR

T2 - applications to dopamine receptor ligands

AU - Nilsson, Jonas

N1 - date_submitted:1998 Rights: University of Groningen

PY - 1998

Y1 - 1998

N2 - There are many opinions about how medicinal chemistry should be practiced. The procedure described in this thesis for the design of new drugs comprises several steps including the selection of a lead compound, experimentald esign, syntheseso f new compounds, pharmacological in vitro testing, molecular modeling and multivariate statistical evaluation. Each step has achieved more or less attention but the main emphasis has been put on the multivariate statistical evaluation. ... Zie: Summary

AB - There are many opinions about how medicinal chemistry should be practiced. The procedure described in this thesis for the design of new drugs comprises several steps including the selection of a lead compound, experimentald esign, syntheseso f new compounds, pharmacological in vitro testing, molecular modeling and multivariate statistical evaluation. Each step has achieved more or less attention but the main emphasis has been put on the multivariate statistical evaluation. ... Zie: Summary

KW - Multivariate analyse

KW - Proefschriften (vorm)

KW - QSAR

KW - Farmacochemie

KW - 44.33

M3 - Thesis fully internal (DIV)

PB - s.n.

ER -

Multiway calibration in 3D QSAR: applications to dopamine receptor ligands

Abstract

Keywords

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