Nanodiamond relaxometry in sperm cells and collective cancer cell migration

    Research output: ThesisThesis fully internal (DIV)

    429 Downloads (Pure)

    Abstract

    This thesis evaluates the biocompatibility of fluorescent nanodiamonds in different sizes and concentrations for two models. The first is boar sperm cells under the capacitation process. And the second model a cervical cancer cell line (HeLa cells) under collective cell migration. From a technical point of view, these two models present a challenge for the current settings as both are dynamic samples requiring spatiotemporal resolution. Furthermore, relaxometry measurements were acquired for the first time in this thesis to detect free radical production in boar sperm cells.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Groningen
    Supervisors/Advisors
    • Schirhagl, Romana, Supervisor
    • Mzyk, Aldona, Co-supervisor
    Award date29-Mar-2023
    Place of Publication[Groningen]
    Publisher
    Print ISBNs978-94-6419-752-5
    DOIs
    Publication statusPublished - 2023

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