Nanogels: A novel approach in antimicrobial delivery systems and antimicrobial coatings

Damla Keskin, Guangyue Zu, Abigail M Forson, Lisa Tromp, Jelmer Sjollema*, Patrick van Rijn*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)
13 Downloads (Pure)

Abstract

The implementation of nanotechnology to develop efficient antimicrobial systems has a significant impact on the prospects of the biomedical field. Nanogels are soft polymeric particles with an internally cross-linked structure, which behave as hydrogels and can be reversibly hydrated/dehydrated (swollen/shrunken) by the dispersing solvent and external stimuli. Their excellent properties, such as biocompatibility, colloidal stability, high water content, desirable mechanical properties, tunable chemical functionalities, and interior gel-like network for the incorporation of biomolecules, make them fascinating in the field of biological/biomedical applications. In this review, various approaches will be discussed and compared to the newly developed nanogel technology in terms of efficiency and applicability for determining their potential role in combating infections in the biomedical area including implant-associated infections.

Original languageEnglish
Pages (from-to)3634-3657
Number of pages24
JournalBioactive Materials
Volume6
Issue number10
DOIs
Publication statusPublished - Oct-2021

Keywords

  • Nanogels
  • Coatings
  • Antibacterial activity
  • Antifouling
  • Biocompatibility
  • CONTROLLED/LIVING RADICAL POLYMERIZATION
  • INVERSE MICROEMULSION POLYMERIZATION
  • DRUG-DELIVERY
  • SILVER NANOPARTICLES
  • ESSENTIAL OILS
  • ACID NANOGEL
  • THERMORESPONSIVE NANOGELS
  • BIOMEDICAL APPLICATIONS
  • VANCOMYCIN RESISTANCE
  • RESPONSIVE NANOGELS

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