BACKGROUND: The purpose of this study was to validate the prognostic value of adding narrow-band imaging (NBI) during transoral laser surgery (TLS) for early glottic cancer.
METHODS: In 84 patients, 93 transoral laser resections were performed for carcinoma in situ (Tcis), T1, or T2 glottic cancer. TLS was preceded by intraoperative evaluation using traditional white-light imaging (WLI) in 51 cases. In 42 cases, NBI was used in addition to WLI. Local recurrence rate and recurrence-free survival were retrospectively compared between both groups.
RESULTS: Local recurrences developed in 14% of the 93 cases: 12 of 51 patients (24%) were treated by TLS based on WLI alone, and in 1 of 42 patients (2%) in the NBI group (P < .01). Two-year recurrence-free survival was 82% in the WLI group and 98% in the NBI group (P < .05).
CONCLUSION: Additional use of NBI during TLS for early glottic cancer significantly improves clinical outcome.
|Number of pages||6|
|Journal||Journal of the Sciences and Specialties of the Head and Neck|
|Early online date||29-Mar-2017|
|Publication status||Published - Jul-2017|
- laryngeal cancer
- narrow-band imaging (NBI)
- transoral laser surgery
- SQUAMOUS-CELL CARCINOMA
- EUROPEAN LARYNGOLOGICAL SOCIETY
- HIGH-DEFINITION TELEVISION
- RESECTION MARGINS
- NASOPHARYNGEAL CARCINOMA