Narrow-band imaging in transoral laser surgery for early glottic cancer in relation to clinical outcome

Boudewijn E C Plaat; Manon A. Zwakenberg; Joost G van Zwol; Jan Wedman; Bernard F A M van der Laan; György B. Halmos; Frederik G Dikkers

doi:10.1002/hed.24773

Narrow-band imaging in transoral laser surgery for early glottic cancer in relation to clinical outcome

Boudewijn E C Plaat, Manon A. Zwakenberg, Joost G van Zwol, Jan Wedman, Bernard F A M van der Laan, György B. Halmos, Frederik G Dikkers

Research output: Contribution to journal › Article › Academic › peer-review

28 Citations (Scopus)

Abstract

BACKGROUND: The purpose of this study was to validate the prognostic value of adding narrow-band imaging (NBI) during transoral laser surgery (TLS) for early glottic cancer.

METHODS: In 84 patients, 93 transoral laser resections were performed for carcinoma in situ (Tcis), T1, or T2 glottic cancer. TLS was preceded by intraoperative evaluation using traditional white-light imaging (WLI) in 51 cases. In 42 cases, NBI was used in addition to WLI. Local recurrence rate and recurrence-free survival were retrospectively compared between both groups.

RESULTS: Local recurrences developed in 14% of the 93 cases: 12 of 51 patients (24%) were treated by TLS based on WLI alone, and in 1 of 42 patients (2%) in the NBI group (P < .01). Two-year recurrence-free survival was 82% in the WLI group and 98% in the NBI group (P < .05).

CONCLUSION: Additional use of NBI during TLS for early glottic cancer significantly improves clinical outcome.

Original language	English
Pages (from-to)	1343-1348
Number of pages	6
Journal	Head and Neck: Journal of the Sciences and Specialties of the Head and Neck
Volume	39
Issue number	7
Early online date	29-Mar-2017
DOIs	https://doi.org/10.1002/hed.24773
Publication status	Published - Jul-2017

Keywords

laryngeal cancer
narrow-band imaging (NBI)
transoral laser surgery
SQUAMOUS-CELL CARCINOMA
EUROPEAN LARYNGOLOGICAL SOCIETY
HIGH-DEFINITION TELEVISION
RESECTION MARGINS
NECK-CANCER
NASOPHARYNGEAL CARCINOMA
LARYNGEAL-CANCER
MICROSURGERY
ENDOSCOPY
HEAD

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Narrow-band imaging in transoral laser surgery forearly glottic cancer in relation to clinical outcome
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Clues for Optimal Use of Narrow Band Imaging in Endoscopic Evaluation of the Larynx and Pharynx: Can We Improve Daily Patient Care?
Plaat, B. (Speaker)
10-Oct-2018
Activity: Talk and presentation › Professional or public presentation › Professional
Narrow band imaging in laryngeal cancer: is it worthwhile?
Plaat, B. (Invited speaker)
28-Jan-2018
Activity: Talk and presentation › Academic presentation › Academic

Cite this

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title = "Narrow-band imaging in transoral laser surgery for early glottic cancer in relation to clinical outcome",

abstract = "BACKGROUND: The purpose of this study was to validate the prognostic value of adding narrow-band imaging (NBI) during transoral laser surgery (TLS) for early glottic cancer.METHODS: In 84 patients, 93 transoral laser resections were performed for carcinoma in situ (Tcis), T1, or T2 glottic cancer. TLS was preceded by intraoperative evaluation using traditional white-light imaging (WLI) in 51 cases. In 42 cases, NBI was used in addition to WLI. Local recurrence rate and recurrence-free survival were retrospectively compared between both groups.RESULTS: Local recurrences developed in 14% of the 93 cases: 12 of 51 patients (24%) were treated by TLS based on WLI alone, and in 1 of 42 patients (2%) in the NBI group (P < .01). Two-year recurrence-free survival was 82% in the WLI group and 98% in the NBI group (P < .05).CONCLUSION: Additional use of NBI during TLS for early glottic cancer significantly improves clinical outcome.",

keywords = "laryngeal cancer, narrow-band imaging (NBI), transoral laser surgery, SQUAMOUS-CELL CARCINOMA, EUROPEAN LARYNGOLOGICAL SOCIETY, HIGH-DEFINITION TELEVISION, RESECTION MARGINS, NECK-CANCER, NASOPHARYNGEAL CARCINOMA, LARYNGEAL-CANCER, MICROSURGERY, ENDOSCOPY, HEAD",

author = "Plaat, {Boudewijn E C} and Zwakenberg, {Manon A.} and {van Zwol}, {Joost G} and Jan Wedman and {van der Laan}, {Bernard F A M} and Halmos, {Gy{\"o}rgy B.} and Dikkers, {Frederik G}",

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year = "2017",

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doi = "10.1002/hed.24773",

language = "English",

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journal = "Head and Neck: Journal of the Sciences and Specialties of the Head and Neck",

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Narrow-band imaging in transoral laser surgery for early glottic cancer in relation to clinical outcome. / Plaat, Boudewijn E C ; Zwakenberg, Manon A.; van Zwol, Joost G et al.
In: Head and Neck: Journal of the Sciences and Specialties of the Head and Neck, Vol. 39, No. 7, 07.2017, p. 1343-1348.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Narrow-band imaging in transoral laser surgery for early glottic cancer in relation to clinical outcome

AU - Plaat, Boudewijn E C

AU - Zwakenberg, Manon A.

AU - van Zwol, Joost G

AU - Wedman, Jan

AU - van der Laan, Bernard F A M

AU - Halmos, György B.

AU - Dikkers, Frederik G

PY - 2017/7

Y1 - 2017/7

N2 - BACKGROUND: The purpose of this study was to validate the prognostic value of adding narrow-band imaging (NBI) during transoral laser surgery (TLS) for early glottic cancer.METHODS: In 84 patients, 93 transoral laser resections were performed for carcinoma in situ (Tcis), T1, or T2 glottic cancer. TLS was preceded by intraoperative evaluation using traditional white-light imaging (WLI) in 51 cases. In 42 cases, NBI was used in addition to WLI. Local recurrence rate and recurrence-free survival were retrospectively compared between both groups.RESULTS: Local recurrences developed in 14% of the 93 cases: 12 of 51 patients (24%) were treated by TLS based on WLI alone, and in 1 of 42 patients (2%) in the NBI group (P < .01). Two-year recurrence-free survival was 82% in the WLI group and 98% in the NBI group (P < .05).CONCLUSION: Additional use of NBI during TLS for early glottic cancer significantly improves clinical outcome.

AB - BACKGROUND: The purpose of this study was to validate the prognostic value of adding narrow-band imaging (NBI) during transoral laser surgery (TLS) for early glottic cancer.METHODS: In 84 patients, 93 transoral laser resections were performed for carcinoma in situ (Tcis), T1, or T2 glottic cancer. TLS was preceded by intraoperative evaluation using traditional white-light imaging (WLI) in 51 cases. In 42 cases, NBI was used in addition to WLI. Local recurrence rate and recurrence-free survival were retrospectively compared between both groups.RESULTS: Local recurrences developed in 14% of the 93 cases: 12 of 51 patients (24%) were treated by TLS based on WLI alone, and in 1 of 42 patients (2%) in the NBI group (P < .01). Two-year recurrence-free survival was 82% in the WLI group and 98% in the NBI group (P < .05).CONCLUSION: Additional use of NBI during TLS for early glottic cancer significantly improves clinical outcome.

KW - laryngeal cancer

KW - narrow-band imaging (NBI)

KW - transoral laser surgery

KW - SQUAMOUS-CELL CARCINOMA

KW - EUROPEAN LARYNGOLOGICAL SOCIETY

KW - HIGH-DEFINITION TELEVISION

KW - RESECTION MARGINS

KW - NECK-CANCER

KW - NASOPHARYNGEAL CARCINOMA

KW - LARYNGEAL-CANCER

KW - MICROSURGERY

KW - ENDOSCOPY

KW - HEAD

U2 - 10.1002/hed.24773

DO - 10.1002/hed.24773

M3 - Article

C2 - 28370672

SN - 1043-3074

VL - 39

SP - 1343

EP - 1348

JO - Head and Neck: Journal of the Sciences and Specialties of the Head and Neck

JF - Head and Neck: Journal of the Sciences and Specialties of the Head and Neck

IS - 7

ER -

Narrow-band imaging in transoral laser surgery for early glottic cancer in relation to clinical outcome

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Clues for Optimal Use of Narrow Band Imaging in Endoscopic Evaluation of the Larynx and Pharynx: Can We Improve Daily Patient Care?

Narrow band imaging in laryngeal cancer: is it worthwhile?

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