Abstract
A novel method of synthesizing solid-phase bound isocyanocarboxylic acids is reported. The potassium salts of four different isocyanocarboxylic acids are coupled onto a brominated resin in DMF in good yields. 32 Ugi reactions were performed using these resins and 24 products were obtained in good to viable purities. © 2003 Elsevier Ltd. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 7015-7018 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 44 |
| Issue number | 37 |
| DOIs | |
| Publication status | Published - 8-Sep-2003 |
Keywords
- carboxylic acid derivative
- isocyanic acid derivative
- potassium salt
- resin
- article
- bromination
- chemical reaction
- solid
- synthesis