New PET technologies: performance, image quality, and clinical implications

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    The most specific and sensitive imaging modality for visualizing and measuring human (patho)physiology in vivo is Positron Emission Tomography (PET). PET is a firmly established biomedical imaging modality with applications in routine clinical diagnostic imaging, but also in research, including clinical trials. Over the past years, PET technology development brought new innovative PET systems to the commercial market: silicon photomultiplier (SiPM)-based or ‘digital’ PET systems, and large axial field-of-view or ‘total body’ PET systems. This thesis describes the technical performance characteristics of these new PET technologies and, in addition, associated optimization of image quality and activity administration is reported. Furthermore, clinical implications and future perspectives regarding these innovations in the field of nuclear medicine and molecular imaging and other medical disciplines are discussed.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Groningen
    • Boellaard, Ronald, Supervisor
    • Noordzij, Walter, Co-supervisor
    • Brouwers, Adrienne, Co-supervisor
    Award date7-Dec-2022
    Place of Publication[Groningen]
    Print ISBNs978-90-832523-2-2
    Electronic ISBNs978-90-832523-3-9
    Publication statusPublished - 2022


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