Nicotinamide compositions and the therapeutic use thereof

Hendrik Jan Cornelis Meijerink (Inventor), Lekhram Changoer (Inventor), Willem Blom (Inventor), Marinella Regina Visser (Inventor), Henderik Willem Frijlink (Inventor), Anko Cornelus Eissens (Inventor)

Research output: Patent

7 Downloads (Pure)


The present invention relates to compositions and methods for the prophylaxis or treatment of deficiencies in essential amino acid absorption and metabolism and/or of a pathology or symptom associated there with. In particular the invention concerns the treatment and/or prevention of ADHD, ADD and autism spectrum disorders. The present inventors have developed a method for prophylaxis or treatment of such symptoms and/or pathologies associated with a deficiency in essential amino acid absorption and/or metabolism, which method, stated generally, relies on the administration of nicotinamide, typically in a long-acting formulation so as to overcome the deficiencies of existing formulations, which have proven unsuitable for effective treatment.

Original languageEnglish
Patent numberWO2013009186
Priority date14/07/2011
Filing date16/07/2012
Publication statusPublished - 17-Jan-2013

Cite this