Noninvasive perilymphatic pressure measurement in patients with Meniere's disease and patients with idiopathic sudden sensorineural hearing loss

HJ Rosingh*, FWJ Albers, HP Wit

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Abstract

Objective: Inner ear disorders are proposed to be affected by changes in inner ear hydrostatic pressure. In humans, the perilymphatic hydrostatic pressure can be assessed in a noninvasive way with the MMS-10 Tympanic Displacement Analyser. In this study, measurements were performed in patients with Meniere's disease and patients with idiopathic sudden sensorineural hearing loss (ISSHL), and the results were compared with those of normal hearing ears. The measurement technique has been evaluated as a possible additional diagnostic tool for Meniere's disease or ISSHL.

Study Design: The hydrostatic perilymphatic pressure was measured noninvasively with the MMS-10 Tympanic Displacement Analyser.

Setting: Department of Otorhinolaryngology at the University Hospital.

Patients: Seventy-seven patients with Meniere's disease, 28 patients with ISSHL, and 50 normal healing subjects.

Intervention: Diagnostic.

Main Outcome Measure: Significant differences of perilymphatic pressure measurement results, represented by the measurement parameters Vi and Vm, in affected, nonaffected and normal hearing ears.

Results: On average, the measurement results showed no significant differences between affected (by Meniere's disease or ISSHL), nonaffected, and normal hearing ears.

Conclusions: In affected tars, perilymphatic pressure measured noninvasively did not differ significantly from the pressure in nonaffected and normal hearing ears. The tympanic membrane displacement technique cannot be considered an additional tool to confirm or reject the diagnosis of Meniere's disease or ISSHL.

Original languageEnglish
Pages (from-to)641-644
Number of pages4
JournalAmerican journal of otology
Volume21
Issue number5
Publication statusPublished - Sept-2000

Keywords

  • Meniere's disease
  • idiopathic sudden sensorineural hearing loss
  • perilymphatic pressure measurement
  • TYMPANIC DISPLACEMENT ANALYZER
  • HYPERTENSION
  • FLUID
  • EAR

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