Novel compositions and methods for trehalose phospholipids

Cheng Tan-Yun (Inventor), Jeffrey Buter (Inventor), Ildiko van Rhijn (Inventor), Adriaan J. Minnaard (Inventor), J. Branch Moody (Inventor)

Research output: Patent

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Abstract

Provided herein are compositions of trehalose phospholipids and uses thereof, e.g., compounds and compositions comprising 6,6'-diphosphatidyltrehalose (diPT) and analogs thereof with modifications of the diPT chemical scaffold, that bind and agonize Mincle, and the use thereof as adjuvants.
Original languageEnglish
Patent numberWO2020146523
Priority date08/01/2019
Filing date08/01/2020
Publication statusPublished - 16-Jul-2020

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