Abstract
Provided herein are compositions of trehalose phospholipids and uses thereof, e.g., compounds and compositions comprising 6,6'-diphosphatidyltrehalose (diPT) and analogs thereof with modifications of the diPT chemical scaffold, that bind and agonize Mincle, and the use thereof as adjuvants.
Original language | English |
---|---|
Patent number | WO2020146523 |
Priority date | 08/01/2019 |
Filing date | 08/01/2020 |
Publication status | Published - 16-Jul-2020 |