Novel Methods towards Rare Sugars Based on Site-Selective Chemistry

    Research output: ThesisThesis fully internal (DIV)

    188 Downloads (Pure)

    Abstract

    Sugars play important roles in the functions of our bodies. Besides common sugars like glucose and lactose, other rare sugars are found in bacteria and other organisms. These rare sugars can have important biological activities, such as anti-cancer, anti-bacterial and anti-viral. Interestingly, these rare sugars can be extremely similar to the common sugars found in mammals and plants. Unfortunately, the chemical synthesis of these sugars from common sugars, despite the similarities between the two, remains challenging. The goal of this thesis is to expand the toolbox on the modification of common sugars, which will eventually lead to the efficient synthesis of useful rare sugars from common sugars.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Groningen
    Supervisors/Advisors
    • Minnaard, Adriaan, Supervisor
    • Witte, Martin, Supervisor
    • Noël, T., Assessment committee, External person
    • van der Marel, G.A., Assessment committee, External person
    • Roelfes, Johannes, Assessment committee
    Award date5-Jan-2021
    Place of Publication[Groningen]
    Publisher
    DOIs
    Publication statusPublished - 2021

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