NSAIDs for Chronic Low Back Pain

Wendy T M Enthoven, Pepijn D Roelofs, Bart W Koes

Research output: Contribution to journalReview articleAcademicpeer-review

29 Citations (Scopus)


Clinical Question: Are nonsteroidal anti-inflammatory drugs (NSAIDs) associated with greater pain relief than placebo, other drugs, and nondrug treatments for patients with chronic low back pain?

Bottom Line: Compared with placebo, NSAIDs are associated with a small but significant improvement in pain and disability in patients with chronic low back pain, although this difference became nonsignificant when studies with high risk for bias were excluded. The associated benefits were smaller than the minimal clinically important difference.

Original languageEnglish
Pages (from-to)2327-2328
Number of pages2
Issue number22
Publication statusPublished - 13-Jun-2017
Externally publishedYes


  • Anti-Inflammatory Agents, Non-Steroidal/therapeutic use
  • Chronic Pain/drug therapy
  • Humans
  • Low Back Pain/drug therapy
  • Placebos/therapeutic use
  • Randomized Controlled Trials as Topic

Cite this