Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

Minseok Kwak; Andreas Herrmann

doi:10.1039/c1cs15138j

Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

Minseok Kwak, Andreas Herrmann^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

161 Citations (Scopus)

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Abstract

This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.

Original language	English
Pages (from-to)	5745-5755
Number of pages	11
Journal	Chemical Society Reviews
Volume	40
Issue number	12
DOIs	https://doi.org/10.1039/c1cs15138j
Publication status	Published - 2011

Keywords

BLOCK-COPOLYMER MICELLES
MODIFIED OLIGONUCLEOTIDES
CYCLOADDITION REACTION
MOLECULAR RECOGNITION
FORCE MICROSCOPY
DNA-ORIGAMI
NANOPARTICLES
SHAPES
FUSION
CHEMISTRY

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title = "Nucleic acid amphiphiles: synthesis and self-assembled nanostructures",

abstract = "This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.",

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author = "Minseok Kwak and Andreas Herrmann",

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language = "English",

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AB - This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.

KW - BLOCK-COPOLYMER MICELLES

KW - MODIFIED OLIGONUCLEOTIDES

KW - CYCLOADDITION REACTION

KW - MOLECULAR RECOGNITION

KW - FORCE MICROSCOPY

KW - DNA-ORIGAMI

KW - NANOPARTICLES

KW - SHAPES

KW - FUSION

KW - CHEMISTRY

U2 - 10.1039/c1cs15138j

DO - 10.1039/c1cs15138j

M3 - Review article

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SP - 5745

EP - 5755

JO - Chemical Society Reviews

JF - Chemical Society Reviews

IS - 12

ER -

Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

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Keywords

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