Obesity and impaired renal function: potential for lifestyle intervention?

Eva Corpeleijn; Stephan J. L. Bakker; Ronald P. Stolk

doi:10.1007/s10654-009-9345-8

Obesity and impaired renal function: potential for lifestyle intervention?

Eva Corpeleijn, Stephan J. L. Bakker, Ronald P. Stolk^*

^*Corresponding author for this work

Research output: Contribution to journal › Editorial › Academic › peer-review

14 Citations (Scopus)

Abstract

Obesity is recently acknowledged as an important independent risk factor for kidney disease, in which epidemiological evidence played a crucial role. This risk is probably explained by intracellular lipid accumulation in the kidney. Lifestyle factors such as physical activity and diet play a role in the development of kidney disease in several stages: development of obesity and the metabolic syndrome, occurrence of obesity-related glomerulopathy, improvement of hemodialysis patients, and prevention of graft dysfunction and graft loss after renal transplantation. After the recent success of lifestyle intervention to prevent diabetes, further research is needed to show the effects of lifestyle changes to prevent and reduce obesity-related morbidity, including chronic kidney disease.

Original language	English
Pages (from-to)	275-280
Number of pages	6
Journal	European Journal of Epidemiology
Volume	24
Issue number	6
DOIs	https://doi.org/10.1007/s10654-009-9345-8
Publication status	Published - Jun-2009

Keywords

Kidney disease
Diabetes
Physical activity
Diet
CHRONIC KIDNEY-DISEASE
BODY-MASS INDEX
GLOMERULAR-FILTRATION-RATE
METABOLIC RISK-FACTORS
TRANSPLANT RECIPIENTS
INSULIN SENSITIVITY
GLUCOSE-TOLERANCE
AEROBIC EXERCISE
SERUM CREATININE
RESISTANCE

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title = "Obesity and impaired renal function: potential for lifestyle intervention?",

abstract = "Obesity is recently acknowledged as an important independent risk factor for kidney disease, in which epidemiological evidence played a crucial role. This risk is probably explained by intracellular lipid accumulation in the kidney. Lifestyle factors such as physical activity and diet play a role in the development of kidney disease in several stages: development of obesity and the metabolic syndrome, occurrence of obesity-related glomerulopathy, improvement of hemodialysis patients, and prevention of graft dysfunction and graft loss after renal transplantation. After the recent success of lifestyle intervention to prevent diabetes, further research is needed to show the effects of lifestyle changes to prevent and reduce obesity-related morbidity, including chronic kidney disease.",

keywords = "Kidney disease, Diabetes, Physical activity, Diet, CHRONIC KIDNEY-DISEASE, BODY-MASS INDEX, GLOMERULAR-FILTRATION-RATE, METABOLIC RISK-FACTORS, TRANSPLANT RECIPIENTS, INSULIN SENSITIVITY, GLUCOSE-TOLERANCE, AEROBIC EXERCISE, SERUM CREATININE, RESISTANCE",

author = "Eva Corpeleijn and Bakker, {Stephan J. L.} and Stolk, {Ronald P.}",

year = "2009",

month = jun,

doi = "10.1007/s10654-009-9345-8",

language = "English",

volume = "24",

pages = "275--280",

journal = "European Journal of Epidemiology",

issn = "0393-2990",

publisher = "Springer",

number = "6",

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TY - JOUR

T1 - Obesity and impaired renal function

T2 - potential for lifestyle intervention?

AU - Corpeleijn, Eva

AU - Bakker, Stephan J. L.

AU - Stolk, Ronald P.

PY - 2009/6

Y1 - 2009/6

N2 - Obesity is recently acknowledged as an important independent risk factor for kidney disease, in which epidemiological evidence played a crucial role. This risk is probably explained by intracellular lipid accumulation in the kidney. Lifestyle factors such as physical activity and diet play a role in the development of kidney disease in several stages: development of obesity and the metabolic syndrome, occurrence of obesity-related glomerulopathy, improvement of hemodialysis patients, and prevention of graft dysfunction and graft loss after renal transplantation. After the recent success of lifestyle intervention to prevent diabetes, further research is needed to show the effects of lifestyle changes to prevent and reduce obesity-related morbidity, including chronic kidney disease.

AB - Obesity is recently acknowledged as an important independent risk factor for kidney disease, in which epidemiological evidence played a crucial role. This risk is probably explained by intracellular lipid accumulation in the kidney. Lifestyle factors such as physical activity and diet play a role in the development of kidney disease in several stages: development of obesity and the metabolic syndrome, occurrence of obesity-related glomerulopathy, improvement of hemodialysis patients, and prevention of graft dysfunction and graft loss after renal transplantation. After the recent success of lifestyle intervention to prevent diabetes, further research is needed to show the effects of lifestyle changes to prevent and reduce obesity-related morbidity, including chronic kidney disease.

KW - Kidney disease

KW - Diabetes

KW - Physical activity

KW - Diet

KW - CHRONIC KIDNEY-DISEASE

KW - BODY-MASS INDEX

KW - GLOMERULAR-FILTRATION-RATE

KW - METABOLIC RISK-FACTORS

KW - TRANSPLANT RECIPIENTS

KW - INSULIN SENSITIVITY

KW - GLUCOSE-TOLERANCE

KW - AEROBIC EXERCISE

KW - SERUM CREATININE

KW - RESISTANCE

U2 - 10.1007/s10654-009-9345-8

DO - 10.1007/s10654-009-9345-8

M3 - Editorial

C2 - 19455406

SN - 0393-2990

VL - 24

SP - 275

EP - 280

JO - European Journal of Epidemiology

JF - European Journal of Epidemiology

IS - 6

ER -

Obesity and impaired renal function: potential for lifestyle intervention?

Abstract

Keywords

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