TY - JOUR
T1 - Observational study of in-hospital mortality risk from bladder cancer
T2 - Five years of experience at a tertiary referral hospital in Indonesia
AU - Djatisoesanto, Wahjoe
AU - Azmi, Yufi Aulia
AU - Yatindra, Ida Bagus Gde Tirta Yoga
AU - Mudjanarko, Sony Wibisono
AU - Umijati, Sri
N1 - Publisher Copyright:
Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.
PY - 2024/8/23
Y1 - 2024/8/23
N2 - Bladder cancer (BC) is a neoplasm arising from the bladder. It requires appropriate management and its prognosis depends on many factors. This study aimed to analyze the factors that influence outcomes in BC management. This was a retrospective study. Data were collected at one of Indonesia's largest tertiary referral hospitals. All patients diagnosed with BC from January 2019 to December 2023 were included. The outcome measured was survival or death. Statistical analysis was conducted using SPSS version 26.0 software. The study included 219 patients with a median age of 57.97 years, of which 99 (45.2 %) patients died. In a bivariate analysis, sex, active smoking status, Karnofsky score, metastasis status, chronic kidney disease, type 2 diabetes mellitus, chemotherapy, radiotherapy, and alternative medicine were found to affect mortality status. Based on multivariate analysis, the route of admission (odds ratio [OR] 0.19), irregular visit (OR 6.21), metastasis (OR 3.58), radiotherapy (OR 21.12), and traditional medicine (OR 0.21) were independent factors of in-hospital mortality. The mortality rate for BC was considerably high. Irregular visits, metastasis, type 2 diabetes, and radiotherapy were independent risk factors for mortality.
AB - Bladder cancer (BC) is a neoplasm arising from the bladder. It requires appropriate management and its prognosis depends on many factors. This study aimed to analyze the factors that influence outcomes in BC management. This was a retrospective study. Data were collected at one of Indonesia's largest tertiary referral hospitals. All patients diagnosed with BC from January 2019 to December 2023 were included. The outcome measured was survival or death. Statistical analysis was conducted using SPSS version 26.0 software. The study included 219 patients with a median age of 57.97 years, of which 99 (45.2 %) patients died. In a bivariate analysis, sex, active smoking status, Karnofsky score, metastasis status, chronic kidney disease, type 2 diabetes mellitus, chemotherapy, radiotherapy, and alternative medicine were found to affect mortality status. Based on multivariate analysis, the route of admission (odds ratio [OR] 0.19), irregular visit (OR 6.21), metastasis (OR 3.58), radiotherapy (OR 21.12), and traditional medicine (OR 0.21) were independent factors of in-hospital mortality. The mortality rate for BC was considerably high. Irregular visits, metastasis, type 2 diabetes, and radiotherapy were independent risk factors for mortality.
KW - bladder cancer
KW - diabetes
KW - in-hospital mortality
KW - oncology
UR - http://www.scopus.com/inward/record.url?scp=85202216070&partnerID=8YFLogxK
U2 - 10.1097/MD.0000000000039412
DO - 10.1097/MD.0000000000039412
M3 - Article
C2 - 39183434
AN - SCOPUS:85202216070
SN - 0025-7974
VL - 103
JO - Medicine
JF - Medicine
IS - 34
M1 - e39412
ER -