@inbook{6f99e8e216dc4969bdc622a4a687cde1,
title = "Opportunities for interfacing organometallic catalysts with cellular metabolism",
abstract = "A concerted effort of synthetic chemistry and synthetic biology promises to expand biological function without the need for extensive genetic manipulation. In such scenarios, man-made catalysts perform new-to-nature transformations on molecules, which are either provided or further diversified by biocatalysts in designer microbes. Here, we highlight the potential of interfacing man-made catalysts with cellular metabolism by discussing the importance of non-enzymatic, metal-catalyzed transformations in nature, means to identify biocompatible transition-metal complexes and their successful integration with cellular metabolism. Lastly, we provide a critical analysis of future prospects and remaining challenges for the applications of biocompatible catalysts in synthetic chemistry, biotechnology, and biomedicine.",
author = "Rudy Rubini and Clemens Mayer",
year = "2022",
month = aug,
day = "5",
doi = "10.1016/B978-0-12-820206-7.00072-X",
language = "English",
isbn = "9780128202067",
volume = "15",
series = "Comprehensive Organometallic Chemistry IV",
pages = "121--145",
editor = "Daumann, {Lena J.}",
booktitle = "Applications IV",
edition = "4",
}