Optimization of the formulation of fast disintegrating tablets

Herman Vincent van Kamp

Optimization of the formulation of fast disintegrating tablets

Herman Vincent van Kamp

Research output: Thesis › Thesis fully internal (DIV)

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Abstract

Chapter 1 presents general information on tableting and is an introduction to the other chapters. Chapter 2 covers the mechanism of action of tablet disintegrants, in particular modern super disintegrants. The results indicate that when the tablets contain a slightly swelling but hydrophilic disintegrant, the penetration of water into tablets is the controlling step in the process of disintegration. Consequently tablet disintegration is strongly affected by the presence of a hydrophobic lubricant. ... Zie: Summary

Original language	English
Qualification	Doctor of Philosophy
Supervisors/Advisors	Doornbos-van Meer, B, Supervisor, External person Lerk, Coenraad, Supervisor
Publisher	s.n.
Publication status	Published - 1987

Keywords

Proefschriften (vorm)
Tabletten, Oplosbaarheid

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@phdthesis{7e55e2f940e2482e8c99d6588291be83,

title = "Optimization of the formulation of fast disintegrating tablets",

abstract = "Chapter 1 presents general information on tableting and is an introduction to the other chapters. Chapter 2 covers the mechanism of action of tablet disintegrants, in particular modern super disintegrants. The results indicate that when the tablets contain a slightly swelling but hydrophilic disintegrant, the penetration of water into tablets is the controlling step in the process of disintegration. Consequently tablet disintegration is strongly affected by the presence of a hydrophobic lubricant. ... Zie: Summary",

keywords = "Proefschriften (vorm), Tabletten, Oplosbaarheid",

author = "Kamp, {Herman Vincent van}",

note = "date_submitted:2008 Rights: University of Groningen",

year = "1987",

language = "English",

publisher = "s.n.",

}

TY - BOOK

T1 - Optimization of the formulation of fast disintegrating tablets

AU - Kamp, Herman Vincent van

N1 - date_submitted:2008 Rights: University of Groningen

PY - 1987

Y1 - 1987

N2 - Chapter 1 presents general information on tableting and is an introduction to the other chapters. Chapter 2 covers the mechanism of action of tablet disintegrants, in particular modern super disintegrants. The results indicate that when the tablets contain a slightly swelling but hydrophilic disintegrant, the penetration of water into tablets is the controlling step in the process of disintegration. Consequently tablet disintegration is strongly affected by the presence of a hydrophobic lubricant. ... Zie: Summary

AB - Chapter 1 presents general information on tableting and is an introduction to the other chapters. Chapter 2 covers the mechanism of action of tablet disintegrants, in particular modern super disintegrants. The results indicate that when the tablets contain a slightly swelling but hydrophilic disintegrant, the penetration of water into tablets is the controlling step in the process of disintegration. Consequently tablet disintegration is strongly affected by the presence of a hydrophobic lubricant. ... Zie: Summary

KW - Proefschriften (vorm)

KW - Tabletten, Oplosbaarheid

M3 - Thesis fully internal (DIV)

PB - s.n.

ER -

Optimization of the formulation of fast disintegrating tablets

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