Oral Appliance Versus Continuous Positive Airway Pressure in Obstructive Sleep Apnea Syndrome: A 2-Year Follow-up

Michiel H. J. Doff*, Aarnoud Hoekema, Peter J. Wijkstra, Johannes H. van der Hoeven, James J. R. Huddleston Slater, Lambert G. M. de Bont, Boudewijn Stegenga

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

103 Citations (Scopus)

Abstract

Study Objectives: Oral appliance therapy has emerged as an important alternative to continuous positive airway pressure (CPAP) in treating patients with obstructive sleep apnea syndrome (OSAS). In this study we report about the subjective and objective treatment outcome of oral appliance therapy and CPAP in patients with OSAS.

Design: Cohort study of a previously conducted randomized clinical trial.

Setting: University Medical Center, Groningen, The Netherlands.

Patients or Participants: One hundred three patients with OSAS.

Interventions: CPAP and oral appliance therapy (Thornton Adjustable Positioner type-1, Airway Management, Inc., Dallas, TX, USA)

Measurements and Results: Objective (polysomnography) and subjective (Epworth Sleepiness Scale, Functional Outcomes of Sleep Questionnaire, Medical Outcomes Study 36-item Short Form Health Survey [SF-36]) parameters were assessed after 1 and 2 years of treatment. Treatment was considered successful when the apnea-hypopnea index (AHI) was

Conclusions: Oral appliance therapy should be considered as a viable treatment alternative to continuous positive airway pressure (CPAP) in patients with mild to moderate obstructive sleep apnea syndrome (OSAS). In patients with severe OSAS, CPAP remains the treatment of first choice.

Clinical Trial Information: The original randomized clinical trial, of which this study is a 2-year follow-up, is registered at ISRCTN.org; identifier: ISRCTN18174167; trial name: Management of the obstructive sleep apnea-hypopnea syndrome: oral appliance versus continuous positive airway pressure therapy; URL: http://www.controlled-trials.com/ISRCTN18174167.

Original languageEnglish
Pages (from-to)1289-1296
Number of pages8
JournalSleep
Volume36
Issue number9
DOIs
Publication statusPublished - 1-Sep-2013

Keywords

  • Continuous positive airway pressure
  • obstructive sleep apnea syndrome
  • oral appliances
  • treatment outcome
  • MANDIBULAR ADVANCEMENT
  • LONG-TERM
  • DENTAL APPLIANCE
  • THERAPY
  • EFFICACY
  • MANAGEMENT

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