TY - JOUR
T1 - Orthostatic hypotension, diabetes, and falling in older patients
T2 - a cross-sectional study
AU - van Hateren, Kornelis J. J.
AU - Kleefstra, Nanne
AU - Blanker, Marco H.
AU - Ubink-Veltmaat, Lielith J.
AU - Groenier, Klaas H.
AU - Houweling, Sebastiaan
AU - Kemper, Adriaan M.
AU - van der Meer, Klaas
AU - Bilo, Henk J. G.
N1 - JID: 9005323; OID: NLM: PMC3459777; PMCR: 2013/10/01 00:00; ppublish
PY - 2012/10/1
Y1 - 2012/10/1
N2 - Background:Although orthostatic hypotension (OH) is more prevalent in old age, and in patients with diabetes, the prevalence of OH in older patients with type 2 diabetes mellitus is unknown.Aim:To establish the prevalence of OH, and its association with falling, in home-dwelling older participants with and without type 2 diabetes.Design and setting:A cross-sectional study in primary care in the Netherlands.Method:A total of 352 patients with type 2 diabetes, and 211 without participated in this study. OH was defined as a fall in blood pressure of at least 20 mmHg systolic or 10 mmHg diastolic after either 1 or 3 minutes in an upright position. Feelings of dizziness, light-headedness, or faintness during the standing period were documented as orthostatic complaints. Fall risk was assessed with a validated risk profile instrument.Results:The prevalence of OH was 28% (95% CI = 24% to 33%) and 18% (95% CI = 13% to 23%) in participants with and without type 2 diabetes, respectively. OH was not related to falling, while the presence of orthostatic complaints in itself was associated with both previous fall incidents as well as a high fall risk, even after adjustment for OH. The adjusted odds ratios were 1.65 (95% CI = 1.00 to 2.72) and 8.21 (95% CI = 4.17 to 16.19), respectively.Conclusion:OH is highly prevalent in home-dwelling older people with and without type 2 diabetes. Those with orthostatic complaints had an increased risk for falling, whereas those with OH were not.
AB - Background:Although orthostatic hypotension (OH) is more prevalent in old age, and in patients with diabetes, the prevalence of OH in older patients with type 2 diabetes mellitus is unknown.Aim:To establish the prevalence of OH, and its association with falling, in home-dwelling older participants with and without type 2 diabetes.Design and setting:A cross-sectional study in primary care in the Netherlands.Method:A total of 352 patients with type 2 diabetes, and 211 without participated in this study. OH was defined as a fall in blood pressure of at least 20 mmHg systolic or 10 mmHg diastolic after either 1 or 3 minutes in an upright position. Feelings of dizziness, light-headedness, or faintness during the standing period were documented as orthostatic complaints. Fall risk was assessed with a validated risk profile instrument.Results:The prevalence of OH was 28% (95% CI = 24% to 33%) and 18% (95% CI = 13% to 23%) in participants with and without type 2 diabetes, respectively. OH was not related to falling, while the presence of orthostatic complaints in itself was associated with both previous fall incidents as well as a high fall risk, even after adjustment for OH. The adjusted odds ratios were 1.65 (95% CI = 1.00 to 2.72) and 8.21 (95% CI = 4.17 to 16.19), respectively.Conclusion:OH is highly prevalent in home-dwelling older people with and without type 2 diabetes. Those with orthostatic complaints had an increased risk for falling, whereas those with OH were not.
KW - RISK-INCREASING DRUGS
KW - BLOOD-PRESSURE
KW - NURSING-HOME
KW - POPULATION
KW - PREVALENCE
KW - PEOPLE
KW - WITHDRAWAL
U2 - 10.3399/bjgp12X656838
DO - 10.3399/bjgp12X656838
M3 - Article
SN - 0960-1643
VL - 62
SP - e696-e702
JO - British Journal of General Practice
JF - British Journal of General Practice
IS - 603
ER -