Pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy

Perrin-Decade Study Grp; Marloes van Gorp; Annet J. Dallmeijer; L. van Wely; Vincent de Groot; Caroline B. Terwee; Gerard Flens; Henk J. Stam; Wilma van der Slot; M. E. Roebroeck; M. E. Roebroeck

doi:10.1080/09638288.2019.1694998

Pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy

Perrin-Decade Study Grp, Marloes van Gorp^*, Annet J. Dallmeijer, L. van Wely, Vincent de Groot, Caroline B. Terwee, Gerard Flens, Henk J. Stam, Wilma van der Slot, M. E. Roebroeck, M. E. Roebroeck

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Purpose: Investigate pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy compared to references. Materials and methods: Young adults with cerebral palsy (n = 97, aged 21-34 years) and age-matched references from the general population (n = 190) rated pain using a numeric rating scale and fatigue, depressive symptoms, sleep disturbance and global health using Patient-Reported Outcomes Measurement Information System (R) short forms. Scores were compared between cerebral palsy subgroups and the reference population. Correlation coefficients and linear regression analyses assessed interrelationships of health issues and associations with global health. Results: Individuals with Gross Motor Function Classification System level I had less pain, fatigue and depressive symptoms, while individuals with levels II and III-V had more pain (53% and 56%, p <0.001) and those with levels III-V more fatigue (39%, p = 0.035) than references (pain: 26%, fatigue: 14%). Pain and fatigue were more interrelated (correlation coefficients: 0.71 vs. 0.41) and stronger associated with global mental health in individuals with cerebral palsy. Conclusions: Young adults with Gross Motor Function Classification System levels II-V report more pain and those with levels III-V report more fatigue than references. Pain and fatigue are highly interrelated and specifically relate to mental health in individuals with cerebral palsy.

Original language	English
Pages (from-to)	2164-2171
Number of pages	8
Journal	Disability and Rehabilitation
Volume	43
Issue number	15
Early online date	6-Dec-2019
DOIs	https://doi.org/10.1080/09638288.2019.1694998
Publication status	Published - Jul-2021

Keywords

Cerebral palsy
young adult
pain
fatigue
depressive symptoms
sleep disturbance
QUALITY-OF-LIFE
CLASSIFICATION-SYSTEM
MUSCULOSKELETAL PAIN
MOTOR FUNCTION
MENTAL-HEALTH
ITEM BANKS
CHILDREN
INDIVIDUALS
GROSS
PARTICIPATION

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Perrin-Decade Study Grp, van Gorp, M., Dallmeijer, A. J., van Wely, L., de Groot, V., Terwee, C. B., Flens, G., Stam, H. J., van der Slot, W., Roebroeck, M. E., & Roebroeck, M. E. (2021). Pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy. Disability and Rehabilitation, 43(15), 2164-2171. https://doi.org/10.1080/09638288.2019.1694998

@article{73698666ed914b889dead203afb925d3,

title = "Pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy",

abstract = "Purpose: Investigate pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy compared to references. Materials and methods: Young adults with cerebral palsy (n = 97, aged 21-34 years) and age-matched references from the general population (n = 190) rated pain using a numeric rating scale and fatigue, depressive symptoms, sleep disturbance and global health using Patient-Reported Outcomes Measurement Information System (R) short forms. Scores were compared between cerebral palsy subgroups and the reference population. Correlation coefficients and linear regression analyses assessed interrelationships of health issues and associations with global health. Results: Individuals with Gross Motor Function Classification System level I had less pain, fatigue and depressive symptoms, while individuals with levels II and III-V had more pain (53% and 56%, p <0.001) and those with levels III-V more fatigue (39%, p = 0.035) than references (pain: 26%, fatigue: 14%). Pain and fatigue were more interrelated (correlation coefficients: 0.71 vs. 0.41) and stronger associated with global mental health in individuals with cerebral palsy. Conclusions: Young adults with Gross Motor Function Classification System levels II-V report more pain and those with levels III-V report more fatigue than references. Pain and fatigue are highly interrelated and specifically relate to mental health in individuals with cerebral palsy.",

keywords = "Cerebral palsy, young adult, pain, fatigue, depressive symptoms, sleep disturbance, QUALITY-OF-LIFE, CLASSIFICATION-SYSTEM, MUSCULOSKELETAL PAIN, MOTOR FUNCTION, MENTAL-HEALTH, ITEM BANKS, CHILDREN, INDIVIDUALS, GROSS, PARTICIPATION",

author = "{Perrin-Decade Study Grp} and {van Gorp}, Marloes and Dallmeijer, {Annet J.} and {van Wely}, L. and {de Groot}, Vincent and Terwee, {Caroline B.} and Gerard Flens and Stam, {Henk J.} and {van der Slot}, Wilma and Roebroeck, {M. E.} and Roebroeck, {M. E.} and {van Gorp}, M. and Tan, {S. S.} and {van Meeteren}, J. and {van der Slot}, W. and H. Stam and Dallmeijer, {A. J.} and {van Wely}, L. and {de Groot}, {Ph. G.} and M. Ketelaar and Voorman, {J. M.} and Reinders-Messelink, {H. A.} and Gorter, {J. W.} and J. Verheijden",

year = "2021",

month = jul,

doi = "10.1080/09638288.2019.1694998",

language = "English",

volume = "43",

pages = "2164--2171",

journal = "Disability and Rehabilitation",

issn = "0963-8288",

publisher = "Taylor & Francis Group",

number = "15",

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TY - JOUR

T1 - Pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy

AU - Perrin-Decade Study Grp

AU - van Gorp, Marloes

AU - Dallmeijer, Annet J.

AU - van Wely, L.

AU - de Groot, Vincent

AU - Terwee, Caroline B.

AU - Flens, Gerard

AU - Stam, Henk J.

AU - van der Slot, Wilma

AU - Roebroeck, M. E.

AU - van Gorp, M.

AU - Tan, S. S.

AU - van Meeteren, J.

AU - van der Slot, W.

AU - Stam, H.

AU - Dallmeijer, A. J.

AU - van Wely, L.

AU - de Groot, Ph. G.

AU - Ketelaar, M.

AU - Voorman, J. M.

AU - Reinders-Messelink, H. A.

AU - Gorter, J. W.

AU - Verheijden, J.

PY - 2021/7

Y1 - 2021/7

N2 - Purpose: Investigate pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy compared to references. Materials and methods: Young adults with cerebral palsy (n = 97, aged 21-34 years) and age-matched references from the general population (n = 190) rated pain using a numeric rating scale and fatigue, depressive symptoms, sleep disturbance and global health using Patient-Reported Outcomes Measurement Information System (R) short forms. Scores were compared between cerebral palsy subgroups and the reference population. Correlation coefficients and linear regression analyses assessed interrelationships of health issues and associations with global health. Results: Individuals with Gross Motor Function Classification System level I had less pain, fatigue and depressive symptoms, while individuals with levels II and III-V had more pain (53% and 56%, p <0.001) and those with levels III-V more fatigue (39%, p = 0.035) than references (pain: 26%, fatigue: 14%). Pain and fatigue were more interrelated (correlation coefficients: 0.71 vs. 0.41) and stronger associated with global mental health in individuals with cerebral palsy. Conclusions: Young adults with Gross Motor Function Classification System levels II-V report more pain and those with levels III-V report more fatigue than references. Pain and fatigue are highly interrelated and specifically relate to mental health in individuals with cerebral palsy.

AB - Purpose: Investigate pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy compared to references. Materials and methods: Young adults with cerebral palsy (n = 97, aged 21-34 years) and age-matched references from the general population (n = 190) rated pain using a numeric rating scale and fatigue, depressive symptoms, sleep disturbance and global health using Patient-Reported Outcomes Measurement Information System (R) short forms. Scores were compared between cerebral palsy subgroups and the reference population. Correlation coefficients and linear regression analyses assessed interrelationships of health issues and associations with global health. Results: Individuals with Gross Motor Function Classification System level I had less pain, fatigue and depressive symptoms, while individuals with levels II and III-V had more pain (53% and 56%, p <0.001) and those with levels III-V more fatigue (39%, p = 0.035) than references (pain: 26%, fatigue: 14%). Pain and fatigue were more interrelated (correlation coefficients: 0.71 vs. 0.41) and stronger associated with global mental health in individuals with cerebral palsy. Conclusions: Young adults with Gross Motor Function Classification System levels II-V report more pain and those with levels III-V report more fatigue than references. Pain and fatigue are highly interrelated and specifically relate to mental health in individuals with cerebral palsy.

KW - Cerebral palsy

KW - young adult

KW - pain

KW - fatigue

KW - depressive symptoms

KW - sleep disturbance

KW - QUALITY-OF-LIFE

KW - CLASSIFICATION-SYSTEM

KW - MUSCULOSKELETAL PAIN

KW - MOTOR FUNCTION

KW - MENTAL-HEALTH

KW - ITEM BANKS

KW - CHILDREN

KW - INDIVIDUALS

KW - GROSS

KW - PARTICIPATION

U2 - 10.1080/09638288.2019.1694998

DO - 10.1080/09638288.2019.1694998

M3 - Article

SN - 0963-8288

VL - 43

SP - 2164

EP - 2171

JO - Disability and Rehabilitation

JF - Disability and Rehabilitation

IS - 15

ER -

Pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy

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Keywords

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