Parotid Gland Biopsy, the Alternative Way to Diagnose Sjogren Syndrome

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Abstract

Salivary gland biopsy is a technique broadly applied for the diagnosis of Sjogren syndrome (SS), lymphoma in SS, and connective tissue disorders (sarcoidosis, amyloidosis). In SS characteristic histology findings are found, including lymphocytic infiltration surrounding the excretory ducts in combination with destruction of acinar tissue. In this article the main techniques are described for taking labial and parotid salivary gland biopsies with respect to their advantages, postoperative complications, and usefulness for diagnostic procedures, monitoring disease progression, and evaluation of treatment.

Original languageEnglish
Pages (from-to)485-499
Number of pages15
JournalRheumatic Disease Clinics of North America
Volume42
Issue number3
DOIs
Publication statusPublished - Aug-2016

Keywords

  • Sjogren syndrome
  • Parotid gland
  • Labial gland
  • Salivary gland
  • Biopsy
  • Diagnostics
  • CLASSIFICATION CRITERIA
  • SALIVARY-GLANDS
  • FIBROMYALGIA SYNDROME
  • RITUXIMAB TREATMENT
  • MALIGNANT-LYMPHOMA
  • LABIAL BIOPSY
  • LIP BIOPSY
  • EFFICACY
  • DISEASE
  • TISSUE

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