Patch testing with rubber series in Europe: A critical review and recommendation

Katharine L. Warburton, Wolfgang Uter, Johannes Geier, Radoslaw Spiewak, Vera Mahler, Marie-Noelle Crepy, Marie Louise Schuttelaar, Andrea Bauer, Mark Wilkinson*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

7 Citations (Scopus)

Abstract

Background. Rubber additives constitute an important group of contact allergens, particularly in certain occupations.

Objectives. To collect information regarding the current practice of using a 'rubber series' in Europe, and discuss this against the background of evidence concerning the prevalence of allergy in order to derive a recommendation for a 'European rubber series'.

Methods. The following were performed: (i) a survey targeting all members of the COST action 'StanDerm' consortium, (ii) analysis of rubber contact allergy data in the database of the European Surveillance System on Contact Allergies, and (iii) a literature review.

Results. Information from 13 countries was available, from one or several departments of dermatology, and occasionally occupational health. Apart from some substances tested only in single departments, a broad overlap regarding important allergens was evident, but considerable variation existed between departments.

Conclusions. An up-to-date 'European rubber series' is recommended, with the exclusion of substances only of historical concern. A 'supplementary rubber series' containing allergens of less proven importance, requiring further analysis, is recommended for departments specializing in occupational contact allergy. These should be continually updated as new evidence emerges.

Original languageEnglish
Pages (from-to)195-203
Number of pages9
JournalCONTACT DERMATITIS
Volume76
Issue number4
Early online date28-Dec-2016
DOIs
Publication statusPublished - Apr-2017

Keywords

  • clinical epidemiology
  • contact allergy
  • patch testing
  • rubber additives
  • standardization
  • ALLERGIC CONTACT-DERMATITIS
  • BASE-LINE SERIES
  • MIXED-DIALKYL-THIOUREAS
  • INFORMATION NETWORK
  • STANDARD SERIES
  • SURVEILLANCE SYSTEM
  • DERMATOLOGY IVDK
  • MERCAPTO-MIX
  • GLOVES
  • MERCAPTOBENZOTHIAZOLE

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