Phenotypic expression of double heterozygosity for BRCA1 and BRCA2 germline mutations

B Leegte; AH van der Hout; AM Deffenbaugh; MK Bakker; IM Mulder; A ten Berge; EP Leenders; J Wesseling; J de Hullu; N Hoogerbrugge; MJL Ligtenberg; A Ardern-Jones; E Bancroft; A Salmon; J Barwell; R Eeles; JC Oosterwijk

doi:10.1136/jmg.2004.027243

Phenotypic expression of double heterozygosity for BRCA1 and BRCA2 germline mutations

B Leegte, AH van der Hout, AM Deffenbaugh, MK Bakker, IM Mulder, A ten Berge, EP Leenders, J Wesseling, J de Hullu, N Hoogerbrugge, MJL Ligtenberg, A Ardern-Jones, E Bancroft, A Salmon, J Barwell, R Eeles, JC Oosterwijk^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

47 Citations (Scopus)

Original language	English
Article number	20
Number of pages	8
Journal	JOURNAL OF MEDICAL GENETICS
Volume	42
Issue number	3
DOIs	https://doi.org/10.1136/jmg.2004.027243
Publication status	Published - Mar-2005

Keywords

OVARIAN-CANCER FAMILIES
2 INDEPENDENT MUTATIONS
ASHKENAZI JEWISH WOMEN
BREAST-CANCER
FOUNDER MUTATIONS
GENE-MUTATIONS
SINGLE-FAMILY
PATIENT
RISK
PENETRANCE

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Leegte, B., van der Hout, AH., Deffenbaugh, AM., Bakker, MK., Mulder, IM., ten Berge, A., Leenders, EP., Wesseling, J., de Hullu, J., Hoogerbrugge, N., Ligtenberg, MJL., Ardern-Jones, A., Bancroft, E., Salmon, A., Barwell, J., Eeles, R., & Oosterwijk, JC. (2005). Phenotypic expression of double heterozygosity for BRCA1 and BRCA2 germline mutations. JOURNAL OF MEDICAL GENETICS, 42(3), [20]. https://doi.org/10.1136/jmg.2004.027243

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author = "B Leegte and {van der Hout}, AH and AM Deffenbaugh and MK Bakker and IM Mulder and {ten Berge}, A and EP Leenders and J Wesseling and {de Hullu}, J and N Hoogerbrugge and MJL Ligtenberg and A Ardern-Jones and E Bancroft and A Salmon and J Barwell and R Eeles and JC Oosterwijk",

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Leegte, B, van der Hout, AH, Deffenbaugh, AM, Bakker, MK, Mulder, IM, ten Berge, A, Leenders, EP, Wesseling, J, de Hullu, J, Hoogerbrugge, N, Ligtenberg, MJL, Ardern-Jones, A, Bancroft, E, Salmon, A, Barwell, J, Eeles, R & Oosterwijk, JC 2005, 'Phenotypic expression of double heterozygosity for BRCA1 and BRCA2 germline mutations', JOURNAL OF MEDICAL GENETICS, vol. 42, no. 3, 20. https://doi.org/10.1136/jmg.2004.027243

TY - JOUR

T1 - Phenotypic expression of double heterozygosity for BRCA1 and BRCA2 germline mutations

AU - Leegte, B

AU - van der Hout, AH

AU - Deffenbaugh, AM

AU - Bakker, MK

AU - Mulder, IM

AU - ten Berge, A

AU - Leenders, EP

AU - Wesseling, J

AU - de Hullu, J

AU - Hoogerbrugge, N

AU - Ligtenberg, MJL

AU - Ardern-Jones, A

AU - Bancroft, E

AU - Salmon, A

AU - Barwell, J

AU - Eeles, R

AU - Oosterwijk, JC

PY - 2005/3

Y1 - 2005/3

KW - OVARIAN-CANCER FAMILIES

KW - 2 INDEPENDENT MUTATIONS

KW - ASHKENAZI JEWISH WOMEN

KW - BREAST-CANCER

KW - FOUNDER MUTATIONS

KW - GENE-MUTATIONS

KW - SINGLE-FAMILY

KW - PATIENT

KW - RISK

KW - PENETRANCE

U2 - 10.1136/jmg.2004.027243

DO - 10.1136/jmg.2004.027243

M3 - Article

VL - 42

JO - JOURNAL OF MEDICAL GENETICS

JF - JOURNAL OF MEDICAL GENETICS

SN - 0022-2593

IS - 3

M1 - 20

ER -