Phylogenetic Evidence for Early Hemochorial Placentation in Eutheria

M. G. Elliot*, B. J. Crespi

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

80 Citations (Scopus)

Abstract

The eutherian placenta is remarkable for its structural and functional variability. In order to construct and test comparative hypotheses relating ecological, behavioral and physiological traits to placental characteristics it is first necessary to reconstruct the historical course of placental evolution. Previous attempts to do so have yielded inconsistent results, particularly with respect to the early evolution of structural relationships between fetal and maternal circulatory systems. Here, we bring a battery of phylogenetic methods - including parsimony, likelihood and Bayesian approaches - to bear on the question of placental evolution. All of these approaches are consistent in indicating that highly invasive hemochorial placentation, as found in human beings and numerous other taxa, was an early evolutionary innovation present in the most ancient ancestors of the living placental mammals. (C) 2009 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)949-967
Number of pages19
JournalPlacenta
Volume30
Issue number11
DOIs
Publication statusPublished - Nov-2009
Externally publishedYes

Keywords

  • Eutheria
  • Comparative methods
  • Placenta
  • Hemochorial
  • Endotheliochorial
  • Epitheliochorial
  • Ancestral state reconstruction
  • CAMEL CAMELUS-DROMEDARIUS
  • PACA AGOUTI-PACA
  • TADARIDA BRASILIENSIS CYNOCEPHALA
  • ELECTRON-MICROSCOPIC OBSERVATIONS
  • SCHREIBERSII-FULIGINOSUS HODGSON
  • MONKEY CERCOPITHECUS-AETHIOPS
  • ELEPHANT LOXODONTA-AFRICANA
  • EARLY EMBRYONIC-DEVELOPMENT
  • CHORIO-ALLANTOIC PLACENTA
  • CROCUTA-CROCUTA ERXLEBEN

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