Placental histopathology after Coxiella burnetii infection during pregnancy

J. M. Munster*, A. C. A. P. Leenders, C. J. C. M. Hamilton, E. Hak, J. G. Aarnoudse, A. Timmer

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)
288 Downloads (Pure)

Abstract

Symptomatic and asymptomatic Coxiella burnetii infection during pregnancy have been associated with obstetric complications. We described placental histopathology and clinical outcome of five cases with asymptomatic C burnetii infection during pregnancy and compared these cases with four symptomatic cases from the literature. In contrast with the symptomatic cases, we did not observe necrosis or active inflammation in the placentas of the asymptomatic women. Obstetrical outcome was more favourable in the asymptomatic cases than in the symptomatic cases. Asymptomatic and symptomatic C. burnetii infection during pregnancy are different entities with respect to placental histopathology and the risk of obstetric complications. (C) 2011 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)128-131
Number of pages4
JournalPlacenta
Volume33
Issue number2
DOIs
Publication statusPublished - Feb-2012

Keywords

  • Q fever
  • Coxiella burnetii
  • Asymptomatic
  • Placental histopathology
  • CHRONIC Q-FEVER
  • NETHERLANDS
  • OUTBREAK
  • THERAPY
  • WOMEN

Cite this