Placental histopathology after Coxiella burnetii infection during pregnancy

J. M. Munster; A. C. A. P. Leenders; C. J. C. M. Hamilton; E. Hak; J. G. Aarnoudse; A. Timmer

doi:10.1016/j.placenta.2011.11.012

Placental histopathology after Coxiella burnetii infection during pregnancy

J. M. Munster^*, A. C. A. P. Leenders, C. J. C. M. Hamilton, E. Hak, J. G. Aarnoudse, A. Timmer

^*Corresponding author for this work

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Abstract

Symptomatic and asymptomatic Coxiella burnetii infection during pregnancy have been associated with obstetric complications. We described placental histopathology and clinical outcome of five cases with asymptomatic C burnetii infection during pregnancy and compared these cases with four symptomatic cases from the literature. In contrast with the symptomatic cases, we did not observe necrosis or active inflammation in the placentas of the asymptomatic women. Obstetrical outcome was more favourable in the asymptomatic cases than in the symptomatic cases. Asymptomatic and symptomatic C. burnetii infection during pregnancy are different entities with respect to placental histopathology and the risk of obstetric complications. (C) 2011 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	128-131
Number of pages	4
Journal	Placenta
Volume	33
Issue number	2
DOIs	https://doi.org/10.1016/j.placenta.2011.11.012
Publication status	Published - Feb-2012

Keywords

Q fever
Coxiella burnetii
Asymptomatic
Placental histopathology
CHRONIC Q-FEVER
NETHERLANDS
OUTBREAK
THERAPY
WOMEN

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title = "Placental histopathology after Coxiella burnetii infection during pregnancy",

abstract = "Symptomatic and asymptomatic Coxiella burnetii infection during pregnancy have been associated with obstetric complications. We described placental histopathology and clinical outcome of five cases with asymptomatic C burnetii infection during pregnancy and compared these cases with four symptomatic cases from the literature. In contrast with the symptomatic cases, we did not observe necrosis or active inflammation in the placentas of the asymptomatic women. Obstetrical outcome was more favourable in the asymptomatic cases than in the symptomatic cases. Asymptomatic and symptomatic C. burnetii infection during pregnancy are different entities with respect to placental histopathology and the risk of obstetric complications. (C) 2011 Elsevier Ltd. All rights reserved.",

keywords = "Q fever, Coxiella burnetii, Asymptomatic, Placental histopathology, CHRONIC Q-FEVER, NETHERLANDS, OUTBREAK, THERAPY, WOMEN",

author = "Munster, {J. M.} and Leenders, {A. C. A. P.} and Hamilton, {C. J. C. M.} and E. Hak and Aarnoudse, {J. G.} and A. Timmer",

year = "2012",

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doi = "10.1016/j.placenta.2011.11.012",

language = "English",

volume = "33",

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journal = "Placenta",

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T1 - Placental histopathology after Coxiella burnetii infection during pregnancy

AU - Munster, J. M.

AU - Leenders, A. C. A. P.

AU - Hamilton, C. J. C. M.

AU - Hak, E.

AU - Aarnoudse, J. G.

AU - Timmer, A.

PY - 2012/2

Y1 - 2012/2

N2 - Symptomatic and asymptomatic Coxiella burnetii infection during pregnancy have been associated with obstetric complications. We described placental histopathology and clinical outcome of five cases with asymptomatic C burnetii infection during pregnancy and compared these cases with four symptomatic cases from the literature. In contrast with the symptomatic cases, we did not observe necrosis or active inflammation in the placentas of the asymptomatic women. Obstetrical outcome was more favourable in the asymptomatic cases than in the symptomatic cases. Asymptomatic and symptomatic C. burnetii infection during pregnancy are different entities with respect to placental histopathology and the risk of obstetric complications. (C) 2011 Elsevier Ltd. All rights reserved.

AB - Symptomatic and asymptomatic Coxiella burnetii infection during pregnancy have been associated with obstetric complications. We described placental histopathology and clinical outcome of five cases with asymptomatic C burnetii infection during pregnancy and compared these cases with four symptomatic cases from the literature. In contrast with the symptomatic cases, we did not observe necrosis or active inflammation in the placentas of the asymptomatic women. Obstetrical outcome was more favourable in the asymptomatic cases than in the symptomatic cases. Asymptomatic and symptomatic C. burnetii infection during pregnancy are different entities with respect to placental histopathology and the risk of obstetric complications. (C) 2011 Elsevier Ltd. All rights reserved.

KW - Q fever

KW - Coxiella burnetii

KW - Asymptomatic

KW - Placental histopathology

KW - CHRONIC Q-FEVER

KW - NETHERLANDS

KW - OUTBREAK

KW - THERAPY

KW - WOMEN

U2 - 10.1016/j.placenta.2011.11.012

DO - 10.1016/j.placenta.2011.11.012

M3 - Article

VL - 33

SP - 128

EP - 131

JO - Placenta

JF - Placenta

IS - 2

ER -

Placental histopathology after Coxiella burnetii infection during pregnancy

Abstract

Keywords

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