TY - JOUR
T1 - Poly(N-isopropylacrylamide) with hydrolyzable lactic acid ester side groups
T2 - A new type of thermosensitive polymer
AU - Neradovic, Dragana
AU - Hinrichs, Wouter L.J.
AU - Kettenes-van Den Bosch, Jantien J.
AU - Hennink, Wim E.
PY - 1999
Y1 - 1999
N2 - N-isopropylacrylamide (NIPAAm) was copolymerized with 2-hydroxyethyl methacrylate-monolactate (HEMA-monolactate). With increasing HEMA-monolactate content in the copolymer, the lower critical solution temperature (LCST) decreases. During incubation in an aqueous solution, the lactate groups are released by hydrolysis, by which the copolymer is converted into poly(NIPAAm-co-HEMA). By this process, the hydrophilicity of the copolymer increases, resulting in increased LCST values.
AB - N-isopropylacrylamide (NIPAAm) was copolymerized with 2-hydroxyethyl methacrylate-monolactate (HEMA-monolactate). With increasing HEMA-monolactate content in the copolymer, the lower critical solution temperature (LCST) decreases. During incubation in an aqueous solution, the lactate groups are released by hydrolysis, by which the copolymer is converted into poly(NIPAAm-co-HEMA). By this process, the hydrophilicity of the copolymer increases, resulting in increased LCST values.
UR - http://www.scopus.com/inward/record.url?scp=22844456871&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1521-3927(19991101)20:11<577::AID-MARC577>3.0.CO;2-D
DO - 10.1002/(SICI)1521-3927(19991101)20:11<577::AID-MARC577>3.0.CO;2-D
M3 - Article
AN - SCOPUS:22844456871
SN - 1022-1336
VL - 20
SP - 577
EP - 581
JO - Macromolecular Rapid Communications
JF - Macromolecular Rapid Communications
IS - 11
ER -