Abstract
Positron emission tomography (PET) is a powerful tool for imaging and quantifying (patho)physiological processes in the human body. PET has been successfully used for staging diseases and evaluating response to treatment. Furthermore, PET may contribute to drug development and individualized treatment planning. This article reviews the use of several PET tracers in drug development and their clinical application in the fields of neurology, oncology and cardiology.
| Original language | English |
|---|---|
| Pages (from-to) | 717-725 |
| Number of pages | 9 |
| Journal | Current Opinion in Drug Discovery & Development |
| Volume | 11 |
| Issue number | 5 |
| Publication status | Published - Sept-2008 |
| Externally published | Yes |
Keywords
- cardiology
- imaging
- neurology
- oncology
- positron emission tomography (PET)
- BLOOD-BRAIN-BARRIER
- ATHEROSCLEROTIC PLAQUE INFLAMMATION
- GLUTAMATE-RECEPTOR SUBTYPE-5
- P-GLYCOPROTEIN TRANSPORT
- PARKINSONS-DISEASE
- CANNABINOID-1 RECEPTOR
- IMAGING PROLIFERATION
- PARAMETRIC METHODS
- PROSTATE-CANCER
- C-11 RACLOPRIDE