POSITRON EMISSION TOMOGRAPHY WITH FLUORINE-18-FLUORODEOXYGLUCOSE FOR THE EVALUATION OF THERAPEUTIC ISOLATED REGIONAL LIMB PERFUSION IN A PATIENT WITH SOFT-TISSUE SARCOMA

OE NIEWEG, J PRUIM, HJ HOEKSTRA, AMJ PAANS, W VAALBURG, J OLDHOFF, HS KOOPS

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

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Abstract

Methods: The treatment of a patient with soft-tissue sarcoma was evaluated with FDG-PET. A limb-saving complete remission of a locally advanced liposarcoma of the left thigh was achieved with isolated regional perfusion of the limb with tumor necrosis factor alpha, interferon gamma and melphalan. Results: PET with F-18-FDG before perfusion showed high glucose consumption in the tumor. After perfusion, glucose metabolism in the tumor was absent. Subsequent excision confirmed complete necrosis of the tumor. Conclusion: FDG-PET may be useful in evaluating the results of isolateral regional limb perfusion for soft-tissue sarcomas.

Original languageEnglish
Pages (from-to)90-92
Number of pages3
JournalJournal of Nuclear Medicine
Volume35
Issue number1
Publication statusPublished - Jan-1994

Keywords

  • FLUORINE-18-FLUORODEOXYGLUCOSE
  • POSITRON EMISSION TOMOGRAPHY
  • GLUCOSE METABOLISM
  • ISOLATED LIMB PERFUSION
  • SARCOMA
  • BRAIN TRANSFER CONSTANTS
  • TIME UPTAKE DATA
  • GRAPHICAL EVALUATION
  • EXTREMITIES
  • CANCER
  • CHEMOTHERAPY
  • COMBINATION
  • TUMORS
  • PET

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