Preliteracy signatures of poor-reading abilities in resting-state EEG

Giuseppina Schiavone, Klaus Linkenkaer-Hansen*, Natasha M. Maurits, Anna Plakas, Ben A. M. Maassen, Huibert D. Mansvelder, Aryan van der Leij, Titia L. van Zuijen

*Corresponding author for this work

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    Abstract

    The hereditary character of dyslexia suggests the presence of putative underlying neural anomalies already in preliterate age. Here, we investigated whether early neurophysiological correlates of future reading difficulties-a hallmark of dyslexia-could be identified in the resting-state EEG of preliterate children. The children in this study were recruited at birth and classified on the basis of parents' performance on reading tests to be at-risk of becoming poor readers (n = 48) or not (n = 14). Eyes-open rest EEG was measured at the age of 3 years, and the at-risk children were divided into fluent readers (n = 24) and non-fluent readers (n = 24) after reading assessment at their third grade of school. We found that fluent readers and non-fluent readers differed in normalized spectral amplitude. Non-fluent readers were characterized by lower amplitude in the delta-1 frequency band (0.5-2 Hz) and higher amplitude in the alpha-1 band (6-8 Hz) in multiple scalp regions compared to control and at-risk fluent readers. Interestingly, across groups these EEG biomarkers correlated with several behavioral test scores measured in the third grade. Specifically, the performance on reading fluency, phonological and orthographic tasks and rapid automatized naming task correlated positively with delta-1 and negatively with alpha-1. Together, our results suggest that combining family-risk status, neurophysiological testing and behavioral test scores in a longitudinal setting may help uncover physiological mechanisms implicated with neurodevelopmental disorders such as the predisposition to reading disabilities.

    Original languageEnglish
    Article number735
    Number of pages11
    JournalFrontiers in Human Neuroscience
    Volume8
    DOIs
    Publication statusPublished - 19-Sep-2014

    Keywords

    • precursors of reading disabilities
    • resting-state EEG
    • reading fluency
    • delta and alpha oscillations
    • RANGE TEMPORAL CORRELATIONS
    • BAND POWER CHANGES
    • DYSLEXIC-CHILDREN
    • DEVELOPMENTAL DYSLEXIA
    • NEURONAL OSCILLATIONS
    • THETA OSCILLATIONS
    • BRAIN MATURATION
    • FAMILIAL RISK
    • SCHOOL-AGE
    • ALPHA

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