PROTEIN CRYSTALS AND THEIR STABILITY

J DRENTH*, C HAAS

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

Abstract

Assuming a simple model, it can be derived that the free energy difference between protein molecules in the crystalline state and in a saturated solution is determined by C(sol)/C(cr), in which C(sol) is the concentration of the protein in the solution and C(cr) that in the crystal. It is estimated that the molecules in the crystalline state are 3-6 kcal/mol more stable than in solution.

Original languageEnglish
Pages (from-to)107-109
Number of pages3
JournalJournal of Crystal Growth
Volume122
Issue number1-4
Publication statusPublished - Aug-1992
Event4TH INTERNATIONAL SYMP ON CRYSTAL GROWTH OF BIOLOGICAL MACROMOLECULES - A FEBS ADVANCED LECTURE COURSE 1991 - , Germany
Duration: 18-Aug-199124-Aug-1991

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