Proteinuria and progression of renal disease: Therapeutic implications

RT Gansevoort; GJ Navis; JH Wapstra; PE de Jong; D de Zeeuw

Proteinuria and progression of renal disease: Therapeutic implications

RT Gansevoort^*, GJ Navis, JH Wapstra, PE de Jong, D de Zeeuw

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

The relationship between proteinuria and progression of renal disease has long been an issue of debate. The present review deals with some of the recent publications on this topic. New concepts are emphasized: the possible causal role of proteinuria in the pathophysiology of progressive renal function loss, and the decrease in urinary protein loss at the beginning of renoprotective therapy as a predictor of renal function outcome during this treatment.

Original language	English
Pages (from-to)	133-140
Number of pages	8
Journal	Current Opinion in Nephrology and Hypertension
Volume	6
Issue number	2
Publication status	Published - Mar-1997

Keywords

GLOMERULAR MESANGIAL CELLS
GLYCOSYLATION END-PRODUCTS
HUMAN DIABETIC NEPHROPATHY
BLOOD-PRESSURE CONTROL
OVERLOAD PROTEINURIA
GLYCATED ALBUMIN
EXPRESSION
RAT
METAANALYSIS
RESTRICTION

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@article{bcb58f8a5da6495085df752ba81aefe0,

title = "Proteinuria and progression of renal disease: Therapeutic implications",

abstract = "The relationship between proteinuria and progression of renal disease has long been an issue of debate. The present review deals with some of the recent publications on this topic. New concepts are emphasized: the possible causal role of proteinuria in the pathophysiology of progressive renal function loss, and the decrease in urinary protein loss at the beginning of renoprotective therapy as a predictor of renal function outcome during this treatment.",

keywords = "GLOMERULAR MESANGIAL CELLS, GLYCOSYLATION END-PRODUCTS, HUMAN DIABETIC NEPHROPATHY, BLOOD-PRESSURE CONTROL, OVERLOAD PROTEINURIA, GLYCATED ALBUMIN, EXPRESSION, RAT, METAANALYSIS, RESTRICTION",

author = "RT Gansevoort and GJ Navis and JH Wapstra and {de Jong}, PE and {de Zeeuw}, D",

year = "1997",

month = mar,

language = "English",

volume = "6",

pages = "133--140",

journal = "Current Opinion in Nephrology and Hypertension",

issn = "1062-4821",

publisher = "Lippincott Williams and Wilkins",

number = "2",

}

TY - JOUR

T1 - Proteinuria and progression of renal disease

T2 - Therapeutic implications

AU - Gansevoort, RT

AU - Navis, GJ

AU - Wapstra, JH

AU - de Jong, PE

AU - de Zeeuw, D

PY - 1997/3

Y1 - 1997/3

N2 - The relationship between proteinuria and progression of renal disease has long been an issue of debate. The present review deals with some of the recent publications on this topic. New concepts are emphasized: the possible causal role of proteinuria in the pathophysiology of progressive renal function loss, and the decrease in urinary protein loss at the beginning of renoprotective therapy as a predictor of renal function outcome during this treatment.

AB - The relationship between proteinuria and progression of renal disease has long been an issue of debate. The present review deals with some of the recent publications on this topic. New concepts are emphasized: the possible causal role of proteinuria in the pathophysiology of progressive renal function loss, and the decrease in urinary protein loss at the beginning of renoprotective therapy as a predictor of renal function outcome during this treatment.

KW - GLOMERULAR MESANGIAL CELLS

KW - GLYCOSYLATION END-PRODUCTS

KW - HUMAN DIABETIC NEPHROPATHY

KW - BLOOD-PRESSURE CONTROL

KW - OVERLOAD PROTEINURIA

KW - GLYCATED ALBUMIN

KW - EXPRESSION

KW - RAT

KW - METAANALYSIS

KW - RESTRICTION

M3 - Review article

SN - 1062-4821

VL - 6

SP - 133

EP - 140

JO - Current Opinion in Nephrology and Hypertension

JF - Current Opinion in Nephrology and Hypertension

IS - 2

ER -

Proteinuria and progression of renal disease: Therapeutic implications

Abstract

Keywords

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