Proteinuria lowering needs a multifactorial and individualized approach to halt progression of renal disease

Paul E. de Jong*, Gerjan Navis

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademicpeer-review

5 Citations (Scopus)

Abstract

This Practice Point commentary discusses the implementation of an intensive, multifactorial intervention in patients who had proteinuria >3g/day despite treatment with angiotensin-converting-enzyme inhibitors. In their 'Remission Clinic' in Bergamo, Italy, Ruggenenti et al. implemented an individual titration regimen using ramipril 5-10 mg/day, losartan 50-100 mg/day, verapamil 80-120 mg/day and atorvastatin 10-20 mg/day in successive steps, aiming for a low blood pressure target of

Original languageEnglish
Pages (from-to)654-655
Number of pages2
JournalNATURE CLINICAL PRACTICE NEPHROLOGY
Volume4
Issue number12
DOIs
Publication statusPublished - Dec-2008

Keywords

  • chronic kidney disease
  • progression
  • proteinuria
  • renoprotective therapy
  • TITRATION
  • RISK

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