TY - JOUR
T1 - Pseudomonas aeruginosa and Staphylococcus aureus virulence factors as biomarkers of infection
AU - Sabat, Artur J
AU - Pantano, Daniele
AU - Akkerboom, Viktoria
AU - Bathoorn, Erik
AU - Friedrich, Alexander W
N1 - © 2021 Artur J. Sabat et al., published by De Gruyter, Berlin/Boston.
PY - 2021/11/25
Y1 - 2021/11/25
N2 - The gold standard for the diagnosis of bacterial infections in clinical samples is based on culture tests that are time-consuming and labor-intense. For these reasons, an extraordinary effort has been made to identify biomarkers as the tools for sensitive, rapid and accurate identification of pathogenic microorganisms. Moreover, biomarkers have been tested to distinguish colonization from infection, monitor disease progression, determine the clinical status of patients or predict clinical outcomes. This mini-review describes Pseudomonas aeruginosa and Staphylococcus aureus biomarkers, which contribute to pathogenesis and have been used in culture-independent bacterial identification directly from patient samples.
AB - The gold standard for the diagnosis of bacterial infections in clinical samples is based on culture tests that are time-consuming and labor-intense. For these reasons, an extraordinary effort has been made to identify biomarkers as the tools for sensitive, rapid and accurate identification of pathogenic microorganisms. Moreover, biomarkers have been tested to distinguish colonization from infection, monitor disease progression, determine the clinical status of patients or predict clinical outcomes. This mini-review describes Pseudomonas aeruginosa and Staphylococcus aureus biomarkers, which contribute to pathogenesis and have been used in culture-independent bacterial identification directly from patient samples.
U2 - 10.1515/hsz-2021-0243
DO - 10.1515/hsz-2021-0243
M3 - Review article
C2 - 34505460
SN - 1437-4315
VL - 402
SP - 1565
EP - 1573
JO - Biological Chemistry
JF - Biological Chemistry
IS - 12
ER -