Python for gene expression

Leonid Bystrykh*

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

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    Abstract

    Genome biology shows substantial progress in its analytical and computational part in the last decades. Differential gene expression is one of many computationally intense areas; it is largely developed under R programming language. Here we explain possible reasons for such dominance of R in gene expression data. Next, we discuss the prospects for Python to become competitive in this area of research in coming years. We indicate that Python can be used already in a field of a single cell differential gene expression. We pinpoint still missing parts in Python and possibilities for improvement.

    Original languageEnglish
    Article number870
    JournalF1000Research
    Volume10
    DOIs
    Publication statusPublished - 2021

    Keywords

    • Differential gene expression
    • Limma
    • Python
    • R
    • Single cell expression

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