Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

TJ Postma*, M Klein, CCP Verstappen, JEC Bromberg, M Swennen, JA Langendijk, MJB Taphoorn, P Scheltens, BJ Slotman, HM van der Ploeg, NK Aaronson, JJ Heimans

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

76 Citations (Scopus)


Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

Original languageEnglish
Pages (from-to)121-123
Number of pages3
Issue number1
Publication statusPublished - 9-Jul-2002


  • MRI
  • CT

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