Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

TJ Postma; M Klein; CCP Verstappen; JEC Bromberg; M Swennen; JA Langendijk; MJB Taphoorn; P Scheltens; BJ Slotman; HM van der Ploeg; NK Aaronson; JJ Heimans

doi:10.1212/WNL.59.1.121

Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

TJ Postma^*, M Klein, CCP Verstappen, JEC Bromberg, M Swennen, JA Langendijk, MJB Taphoorn, P Scheltens, BJ Slotman, HM van der Ploeg, NK Aaronson, JJ Heimans

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

Original language	English
Pages (from-to)	121-123
Number of pages	3
Journal	Neurology
Volume	59
Issue number	1
DOIs	https://doi.org/10.1212/WNL.59.1.121
Publication status	Published - 9-Jul-2002

Keywords

MRI
CT

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title = "Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma",

abstract = "Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.",

keywords = "MRI, CT",

author = "TJ Postma and M Klein and CCP Verstappen and JEC Bromberg and M Swennen and JA Langendijk and MJB Taphoorn and P Scheltens and BJ Slotman and {van der Ploeg}, HM and NK Aaronson and JJ Heimans",

year = "2002",

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doi = "10.1212/WNL.59.1.121",

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TY - JOUR

T1 - Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

AU - Postma, TJ

AU - Klein, M

AU - Verstappen, CCP

AU - Bromberg, JEC

AU - Swennen, M

AU - Langendijk, JA

AU - Taphoorn, MJB

AU - Scheltens, P

AU - Slotman, BJ

AU - van der Ploeg, HM

AU - Aaronson, NK

AU - Heimans, JJ

PY - 2002/7/9

Y1 - 2002/7/9

N2 - Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

AB - Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

KW - MRI

KW - CT

U2 - 10.1212/WNL.59.1.121

DO - 10.1212/WNL.59.1.121

M3 - Article

SN - 0028-3878

VL - 59

SP - 121

EP - 123

JO - Neurology

JF - Neurology

IS - 1

ER -

Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

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