Reanalysis of Vedhara et al. 's (2015) study of personality and gene expression

Nicholas J. L. Brown; Carol A. Nickerson

doi:10.1016/j.paid.2015.11.055

Reanalysis of Vedhara et al. 's (2015) study of personality and gene expression

Nicholas J. L. Brown^*, Carol A. Nickerson

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

Abstract

A recent study by Vedhara et al. appearing in Psychoneuroendocrinology (2015,52, 72-82) concluded that the personality traits of conscientiousness and extraversion were associated with the decreased and increased expression of pro-inflammatory genes, respectively. A reanalysis of the data from this study indicates that these results are fragile and ambiguous, and depend on (a) the inclusion or exclusion of two study participants missing values for one of the control variables and (b) the accumulation of statistical suppression effects in the regression analyses. (C) 2015 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	133-137
Number of pages	5
Journal	Personality and Individual Differences
Volume	91
DOIs	https://doi.org/10.1016/j.paid.2015.11.055
Publication status	Published - Mar-2016

Keywords

Gene expression
Immunity
Personality
Pro-inflammatory
SITUATIONS

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title = "Reanalysis of Vedhara et al. 's (2015) study of personality and gene expression",

abstract = "A recent study by Vedhara et al. appearing in Psychoneuroendocrinology (2015,52, 72-82) concluded that the personality traits of conscientiousness and extraversion were associated with the decreased and increased expression of pro-inflammatory genes, respectively. A reanalysis of the data from this study indicates that these results are fragile and ambiguous, and depend on (a) the inclusion or exclusion of two study participants missing values for one of the control variables and (b) the accumulation of statistical suppression effects in the regression analyses. (C) 2015 Elsevier Ltd. All rights reserved.",

keywords = "Gene expression, Immunity, Personality, Pro-inflammatory, SITUATIONS",

author = "Brown, {Nicholas J. L.} and Nickerson, {Carol A.}",

year = "2016",

month = mar,

doi = "10.1016/j.paid.2015.11.055",

language = "English",

volume = "91",

pages = "133--137",

journal = "Personality and Individual Differences",

issn = "0191-8869",

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T1 - Reanalysis of Vedhara et al. 's (2015) study of personality and gene expression

AU - Brown, Nicholas J. L.

AU - Nickerson, Carol A.

PY - 2016/3

Y1 - 2016/3

N2 - A recent study by Vedhara et al. appearing in Psychoneuroendocrinology (2015,52, 72-82) concluded that the personality traits of conscientiousness and extraversion were associated with the decreased and increased expression of pro-inflammatory genes, respectively. A reanalysis of the data from this study indicates that these results are fragile and ambiguous, and depend on (a) the inclusion or exclusion of two study participants missing values for one of the control variables and (b) the accumulation of statistical suppression effects in the regression analyses. (C) 2015 Elsevier Ltd. All rights reserved.

AB - A recent study by Vedhara et al. appearing in Psychoneuroendocrinology (2015,52, 72-82) concluded that the personality traits of conscientiousness and extraversion were associated with the decreased and increased expression of pro-inflammatory genes, respectively. A reanalysis of the data from this study indicates that these results are fragile and ambiguous, and depend on (a) the inclusion or exclusion of two study participants missing values for one of the control variables and (b) the accumulation of statistical suppression effects in the regression analyses. (C) 2015 Elsevier Ltd. All rights reserved.

KW - Gene expression

KW - Immunity

KW - Personality

KW - Pro-inflammatory

KW - SITUATIONS

U2 - 10.1016/j.paid.2015.11.055

DO - 10.1016/j.paid.2015.11.055

M3 - Review article

SN - 0191-8869

VL - 91

SP - 133

EP - 137

JO - Personality and Individual Differences

JF - Personality and Individual Differences

ER -

Reanalysis of Vedhara et al. 's (2015) study of personality and gene expression

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Keywords

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