Abstract
In this critical review, the progress in catalytic asymmetric synthesis of β-amino acids is discussed, covering the literature since 2002. The review treats transition metal catalysis, organocatalysis and biocatalysis and covers the most important synthetic methods, such as hydrogenation, the Mannich reaction and conjugate additions.
| Original language | English |
|---|---|
| Pages (from-to) | 1656-1691 |
| Number of pages | 36 |
| Journal | Chemical Society Reviews |
| Volume | 39 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2010 |
Keywords
- MANNICH-TYPE REACTIONS
- ENANTIOSELECTIVE CONJUGATE ADDITION
- CHIRAL BRONSTED ACID
- TRANSITION-METAL CATALYSIS
- HIGHLY EFFICIENT SYNTHESIS
- BAYLIS-HILLMAN REACTION
- AZA-MICHAEL REACTION
- ONE-POT PROCEDURE
- BETA(2)-AMINO ACIDS
- ALPHA-AMINO
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