Recombinant Gelatin Microspheres: Novel Formulations for Tissue Repair?

Annemarie Tuin*, Sebastiaan G. Kluijtmans, Jan B. Bouwstra, Martin C. Harmsen, Marja J. A. Van Luyn

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

Abstract

Microspheres (MSs) can function as multifunctional scaffolds in different approaches of tissue repair (TR), as a filler, a slow-release depot for growth factors, or a delivery vehicle for cells. Natural cell adhesion-supporting extracellular matrix components like gelatin are good materials for these purposes. Recombinant production of gelatin allows for on-demand design of gelatins, which is why we aim at developing recombinant gelatin (RG) MSs for TR. Two types of MSs (50

Original languageEnglish
Pages (from-to)1811-1821
Number of pages11
JournalTissue Engineering. Part A
Volume16
Issue number6
DOIs
Publication statusPublished - Jun-2010

Keywords

  • FOREIGN-BODY REACTION
  • IN-VIVO
  • MATRIX METALLOPROTEINASES
  • GENE-EXPRESSION
  • STEM-CELLS
  • DELIVERY
  • SCAFFOLDS
  • TRANSPLANTATION
  • KERATINOCYTES
  • BIOMATERIALS

Cite this