Relationship of corneal hysteresis and optic nerve parameters in healthy myopic subjects

Kunliang Qiu, Riping Zhang, Geng Wang, Mingzhi Zhang*

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    3 Citations (Scopus)
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    Abstract

    The association between corneal biomechanical properties and glaucoma is an area of much interest. We determined the relationship between corneal hysteresis (CH) and optic nerve parameters in healthy myopic subjects in the current study. CH was measured with Reichert Ocular Response Analyzer in 108 eyes from 108 healthy myopic subjects. All subjects received retinal nerve fiber layer and optic disc imaging Cirrus HD-OCT, GDx ECC, and Heidelberg Retina Tomograph II. None of the tested optic nerve parameters showed statistical significance with CH by using correlation analysis. For RNFL parameters, there was a negative but not statistically significant correlation between CH and average RNFL thickness obtained with OCT (r = -0.15, p = 0.13). For optic disc parameters, there was a negative but not statistically significant correlation between CH and rim area measured with OCT (r = -0.10, p = 0.29). The current study did not find any statistically significant relationship between CH and optic nerve parameters as measured by all three imaging modalities in healthy myopic eyes. Therefore, the relationship observed previously in glaucoma subjects is likely coming to fruition as optic nerve damage is caused by the disease.

    Original languageEnglish
    Article number17538
    Number of pages7
    JournalScientific Reports
    Volume7
    DOIs
    Publication statusPublished - 13-Dec-2017

    Keywords

    • OPEN-ANGLE GLAUCOMA
    • FIBER LAYER
    • BIOMECHANICAL PROPERTIES
    • DISC MORPHOLOGY
    • RISK-FACTORS
    • THICKNESS
    • POPULATION
    • CHILDREN
    • EYES

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