Abstract
2012 saw the classification of the systemic vasculitides revised. Genetic studies showed that granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are different diseases with aberrant immune responses to different autoantigens. B-cell depletion with rituximab also acquired a primary role in the treatment of GPA and MPA, as well as in cryoglobulinaemic vasculitis. Kallenberg, C. G. M. Nat. Rev. Nephrol. 9, 70-72 (2013); published online 8 January 2013; doi:10.1038/nrneph.2012.284
Original language | English |
---|---|
Pages (from-to) | 70-72 |
Number of pages | 3 |
Journal | Nature Reviews Nephrology |
Volume | 9 |
Issue number | 2 |
DOIs | |
Publication status | Published - Feb-2013 |
Keywords
- ANCA-ASSOCIATED VASCULITIS
- ANTIBODY-ASSOCIATED VASCULITIS
- DAILY ORAL CYCLOPHOSPHAMIDE
- REMISSION INDUCTION
- RANDOMIZED-TRIAL
- RITUXIMAB
- MAINTENANCE
- PULSE