RENAL VASCULITIS IN 2012 Reclassification and the introduction of biologicals

Cees G. M. Kallenberg*

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademicpeer-review

3 Citations (Scopus)

Abstract

2012 saw the classification of the systemic vasculitides revised. Genetic studies showed that granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are different diseases with aberrant immune responses to different autoantigens. B-cell depletion with rituximab also acquired a primary role in the treatment of GPA and MPA, as well as in cryoglobulinaemic vasculitis. Kallenberg, C. G. M. Nat. Rev. Nephrol. 9, 70-72 (2013); published online 8 January 2013; doi:10.1038/nrneph.2012.284

Original languageEnglish
Pages (from-to)70-72
Number of pages3
JournalNature Reviews Nephrology
Volume9
Issue number2
DOIs
Publication statusPublished - Feb-2013

Keywords

  • ANCA-ASSOCIATED VASCULITIS
  • ANTIBODY-ASSOCIATED VASCULITIS
  • DAILY ORAL CYCLOPHOSPHAMIDE
  • REMISSION INDUCTION
  • RANDOMIZED-TRIAL
  • RITUXIMAB
  • MAINTENANCE
  • PULSE

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