Respiratory ammonia output and blood ammonia concentration during incremental exercise

W Ament*, [No Value] Huizenga, E Kort, TW van der Mark, RG Grevink, GJ Verkerke

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

43 Citations (Scopus)

Abstract

The aim of this study was to investigate whether the increase of ammonia concentration and lactate concentration in blood was accompanied by an increased expiration of ammonia during graded exercise. Eleven healthy subjects performed an incremental cycle ergometer test. Blood ammonia, blood lactate and the amount of expired ammonia were measured until 30 minutes post exercise. The expired air was guided through a flow chamber filled with a sulphuric acid solution to trap the expired ammonia. Blood ammonia, blood lactate increased more than proportionally and the amount of expired ammonia tin mu mol/min) increased exponentially with the workload. Postexercise the amount of expired ammonia decreased within a few minutes back to pre-exercise levels while the concentrations of lactate and ammonia in blood decreased much more slowly and were still elevated after 30 minutes of recovery. We conclude that the more than proportional increase of ammonia and lactate during graded exercise, is accompanied with an exponential increase of expired ammonia output. Faster and more accurate ammonia gas detection techniques are necessary to quantify more precisely the respiratory ammonia output during graded exercise.

Original languageEnglish
Pages (from-to)71-77
Number of pages7
JournalInternational Journal of Sports Medicine
Volume20
Issue number2
Publication statusPublished - Feb-1999

Keywords

  • ammonia expiration
  • blood ammonia
  • incremental exercise
  • ERGOMETER EXERCISE
  • LACTATE

Cite this