Response time of nanofluidic electrochemical sensors

Shuo Kang, Klaus Mathwig, Serge G. Lemay*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Scopus)


Nanofluidic thin-layer cells count among the most sensitive electrochemical sensors built to date. Here we study both experimentally and theoretically the factors that limit the response time of these sensors. We find that the key limiting factor is reversible adsorption of the analyte molecules to the surfaces of the nanofluidic system, a direct consequence of its high surface-to-volume ratio. Our results suggest several means of improving the response time of the sensor, including optimizing the device geometry and tuning the electrode biasing scheme so as to minimize adsorption.

Original languageEnglish
Pages (from-to)1262-1267
Number of pages6
JournalLab on a Chip - Miniaturisation for Chemistry and Biology
Issue number7
Publication statusPublished - 2012
Externally publishedYes



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