Retriever fetches integrins from endosomes

Catherine Rabouille*

*Corresponding author for this work

    Research output: Contribution to journalEditorialAcademicpeer-review

    2 Citations (Scopus)

    Abstract

    Recycling from endosomes to the plasma membrane is an important step in cell homeostasis. The retromer/SNX27/WASH complex recycles numerous receptors, but key ones are still unaccounted for. Now a related conserved heterotrimer, called retriever, has been identified that, together with SNX17, the CCC complex and WASH, mediates the recycling of α(5)β(1) integrins.

    Original languageEnglish
    Pages (from-to)1144-1146
    Number of pages3
    JournalNature Cell Biology
    Volume19
    Issue number10
    DOIs
    Publication statusPublished - Oct-2017

    Keywords

    • TRANS-GOLGI NETWORK
    • RETROGRADE TRANSPORT
    • RETROMER
    • COMPLEX
    • DEGRADATION
    • TRAFFICKING
    • RECOGNITION

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