Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids

R.B.C. Jagt; P.Y. Toullec; J.G. de Vries; B.L. Feringa; A.J. Minnaard

doi:10.1039/b518311a

Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids

R.B.C. Jagt
, P.Y. Toullec
, J.G. de Vries
, B.L. Feringa
, A.J. Minnaard

Research output: Contribution to journal › Article › Academic › peer-review

77 Citations (Scopus)

Abstract

Phosphoramidites are effective chiral ligands in the rhodium catalyzed addition of arylboronic acids to aldehydes providing up to 75% enantioselectivity and up to 96% isolated yield.

Original language	English
Pages (from-to)	773-775
Number of pages	3
Journal	Organic & Biomolecular Chemistry
Volume	4
Issue number	5
DOIs	https://doi.org/10.1039/b518311a
Publication status	Published - 2006

Keywords

C BOND FORMATION
MONODENTATE PHOSPHORAMIDITES
ARYL TRANSFER
ENANTIOSELECTIVE SYNTHESIS
CONJUGATE ADDITION
CARBONYL-COMPOUNDS
LIGAND LIBRARIES
BORONIC ACIDS
DERIVATIVES

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Rhodium-phosphoramidite-catalyzed asymmetric arylation of aldehydes
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title = "Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids",

abstract = "Phosphoramidites are effective chiral ligands in the rhodium catalyzed addition of arylboronic acids to aldehydes providing up to 75\% enantioselectivity and up to 96\% isolated yield.",

keywords = "C BOND FORMATION, MONODENTATE PHOSPHORAMIDITES, ARYL TRANSFER, ENANTIOSELECTIVE SYNTHESIS, CONJUGATE ADDITION, CARBONYL-COMPOUNDS, LIGAND LIBRARIES, BORONIC ACIDS, DERIVATIVES",

author = "R.B.C. Jagt and P.Y. Toullec and \{de Vries\}, J.G. and B.L. Feringa and A.J. Minnaard",

year = "2006",

doi = "10.1039/b518311a",

language = "English",

volume = "4",

pages = "773--775",

journal = "Organic \& Biomolecular Chemistry",

issn = "1477-0520",

publisher = "ROYAL SOC CHEMISTRY",

number = "5",

}

TY - JOUR

T1 - Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids

AU - Jagt, R.B.C.

AU - Toullec, P.Y.

AU - de Vries, J.G.

AU - Feringa, B.L.

AU - Minnaard, A.J.

PY - 2006

Y1 - 2006

N2 - Phosphoramidites are effective chiral ligands in the rhodium catalyzed addition of arylboronic acids to aldehydes providing up to 75% enantioselectivity and up to 96% isolated yield.

AB - Phosphoramidites are effective chiral ligands in the rhodium catalyzed addition of arylboronic acids to aldehydes providing up to 75% enantioselectivity and up to 96% isolated yield.

KW - C BOND FORMATION

KW - MONODENTATE PHOSPHORAMIDITES

KW - ARYL TRANSFER

KW - ENANTIOSELECTIVE SYNTHESIS

KW - CONJUGATE ADDITION

KW - CARBONYL-COMPOUNDS

KW - LIGAND LIBRARIES

KW - BORONIC ACIDS

KW - DERIVATIVES

U2 - 10.1039/b518311a

DO - 10.1039/b518311a

M3 - Article

SN - 1477-0520

VL - 4

SP - 773

EP - 775

JO - Organic & Biomolecular Chemistry

JF - Organic & Biomolecular Chemistry

IS - 5

ER -

Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids

Abstract

Keywords

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