Risicofactoren voor medicatiefouten na eerdere medicatieverificatie bij electieve opnames

Translated title of the contribution: Risk factors for medication erros at admission in preoperatively screened patients

M.M. Ebbens*, K.B. Gombert-Handoko, M. Al-Dulaimy, P.M.L.A. van den Bemt, E.J. Wesselink

*Corresponding author for this work

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Preoperative screening (POS) may help to reduce medication errors at admission (MEA). However, due to the time window between POS and hospital admission, unintentional medication discrepancies may still occur and thus a second medication reconciliation at hospital admission is necessary. Insight into potential risk factors associated with these discrepancies would be helpful to focus the second medication reconciliation on high risk patients.


To determine the occurrence of MEA and to identify risk factors for MEA in preoperatively screened patients.


This single-centre observational cross-sectional study included elective surgical patients between 26 October and 18 December 2015. Main inclusion criteria were age ≥18 years and elective non-day care admissions. Medication reconciliation took place at the preoperative screening and was repeated within 30 hours of admission. Unintended discrepancies between the first and second medication reconciliation were defined as MEA. The primary outcome was the occurrence of MEA in preoperatively screened patients. The association of this outcome with potential risk factors was analysed using multivariate logistic regression analysis.


Of the 183 included patients 60 (33%) patients had at least one MEA. In a multivariate model the number of medications at POS (adjusted odds ratio 1.16, 95%-confidence interval [95%-CI] 1.04-1.30), and respiratory disease (odds ratio 4.25, 95%-CI 1.52-11.83) were significantly associated with MEA.


In our study MEA occurred in 33% of preoperatively screened patients. Polypharmacy and respiratory comorbidities are risk factors for MEA in preoperatively screened patients.
Translated title of the contributionRisk factors for medication erros at admission in preoperatively screened patients
Original languageDutch
Article numbera1661
JournalNederlands Platform voor Farmaceutisch Onderzoek
Issue number3
Publication statusPublished - Jan-2018
Externally publishedYes

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