RNA dynamics from experimental and computational approaches

Giovanni Bussi; Massimiliano Bonomi; Paraskevi Gkeka; Michael Sattler; Hashim M Al-Hashimi; Pascal Auffinger; Maria Duca; Yann Foricher; Danny Incarnato; Alisha N Jones; Serdal Kirmizialtin; Miroslav Krepl; Modesto Orozco; Giulia Palermo; Samuela Pasquali; Loïc Salmon; Harald Schwalbe; Eric Westhof; Martin Zacharias

doi:10.1016/j.str.2024.07.019

RNA dynamics from experimental and computational approaches

Giovanni Bussi^*, Massimiliano Bonomi^*, Paraskevi Gkeka^*, Michael Sattler^*, Hashim M Al-Hashimi, Pascal Auffinger, Maria Duca, Yann Foricher, Danny Incarnato, Alisha N Jones, Serdal Kirmizialtin, Miroslav Krepl, Modesto Orozco, Giulia Palermo, Samuela Pasquali, Loïc Salmon, Harald Schwalbe, Eric Westhof, Martin Zacharias

^*Corresponding author for this work

Molecular Genetics

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Conformational dynamics is crucial for the biological function of RNA molecules and for their potential as therapeutic targets. This meeting report outlines key "take-home" messages that emerged from the presentations and discussions during the CECAM workshop "RNA dynamics from experimental and computational approaches" in Paris, June 26-28, 2023.

Original language	English
Pages (from-to)	1281-1287
Number of pages	7
Journal	Structure
Volume	32
Issue number	9
DOIs	https://doi.org/10.1016/j.str.2024.07.019
Publication status	Published - 5-Sept-2024

Keywords

Nucleic Acid Conformation
RNA/metabolism
Molecular Dynamics Simulation
Computational Biology/methods
Humans

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Bussi, G., Bonomi, M., Gkeka, P., Sattler, M., Al-Hashimi, H. M., Auffinger, P., Duca, M., Foricher, Y., Incarnato, D., Jones, A. N., Kirmizialtin, S., Krepl, M., Orozco, M., Palermo, G., Pasquali, S., Salmon, L., Schwalbe, H., Westhof, E., & Zacharias, M. (2024). RNA dynamics from experimental and computational approaches. Structure, 32(9), 1281-1287. https://doi.org/10.1016/j.str.2024.07.019

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Bussi, G, Bonomi, M, Gkeka, P, Sattler, M, Al-Hashimi, HM, Auffinger, P, Duca, M, Foricher, Y, Incarnato, D, Jones, AN, Kirmizialtin, S, Krepl, M, Orozco, M, Palermo, G, Pasquali, S, Salmon, L, Schwalbe, H, Westhof, E & Zacharias, M 2024, 'RNA dynamics from experimental and computational approaches', Structure, vol. 32, no. 9, pp. 1281-1287. https://doi.org/10.1016/j.str.2024.07.019

TY - JOUR

T1 - RNA dynamics from experimental and computational approaches

AU - Bussi, Giovanni

AU - Bonomi, Massimiliano

AU - Gkeka, Paraskevi

AU - Sattler, Michael

AU - Al-Hashimi, Hashim M

AU - Auffinger, Pascal

AU - Duca, Maria

AU - Foricher, Yann

AU - Incarnato, Danny

AU - Jones, Alisha N

AU - Kirmizialtin, Serdal

AU - Krepl, Miroslav

AU - Orozco, Modesto

AU - Palermo, Giulia

AU - Pasquali, Samuela

AU - Salmon, Loïc

AU - Schwalbe, Harald

AU - Westhof, Eric

AU - Zacharias, Martin

PY - 2024/9/5

Y1 - 2024/9/5

N2 - Conformational dynamics is crucial for the biological function of RNA molecules and for their potential as therapeutic targets. This meeting report outlines key "take-home" messages that emerged from the presentations and discussions during the CECAM workshop "RNA dynamics from experimental and computational approaches" in Paris, June 26-28, 2023.

AB - Conformational dynamics is crucial for the biological function of RNA molecules and for their potential as therapeutic targets. This meeting report outlines key "take-home" messages that emerged from the presentations and discussions during the CECAM workshop "RNA dynamics from experimental and computational approaches" in Paris, June 26-28, 2023.

KW - Nucleic Acid Conformation

KW - RNA/metabolism

KW - Molecular Dynamics Simulation

KW - Computational Biology/methods

KW - Humans

U2 - 10.1016/j.str.2024.07.019

DO - 10.1016/j.str.2024.07.019

M3 - Article

C2 - 39241758

SN - 1878-4186

VL - 32

SP - 1281

EP - 1287

JO - Structure

JF - Structure

IS - 9

ER -

RNA dynamics from experimental and computational approaches

Abstract

Keywords

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