Abstract
This paper reviews the literature from 1988 to November 1993 on the effectiveness of routine vaccination of HIV-infected adults. Data on the clinical benefit of vaccination in this particular group of patients are not available. In general, HIV-infected patients have suboptimal immunological responses to vaccines. In particular, an impaired responsiveness is found in patients with fewer than 200 x 10(6) CD4 + cells per litre. Consequently, it seems prudent to offer active immunization to HIV-infected subjects who are relatively immunocompetent. However, the usefulness of vaccination in those subjects who have a low CD4 + cell count is doubtful.
| Original language | English |
|---|---|
| Pages (from-to) | 244-249 |
| Number of pages | 6 |
| Journal | The Netherlands Journal of Medicine |
| Volume | 45 |
| Issue number | 6 |
| Publication status | Published - Dec-1994 |
| Externally published | Yes |
Keywords
- HIV
- AIDS
- IMMUNODEFICIENCY
- VACCINATION
- HUMAN-IMMUNODEFICIENCY-VIRUS
- HEPATITIS-B VACCINATION
- ANTIBODY-RESPONSES
- CAPSULAR POLYSACCHARIDES
- PNEUMOCOCCAL VACCINE
- MEN
- MEASLES