Saccharide-Containing Dynamic Proteoids

Yun Liu, Marc Stuart, Martin Witte, Eric Buhler, Anna Katharina Herta Hirsch

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
196 Downloads (Pure)

Abstract

Dynamic proteoids are dynamic covalent analogues of proteins which can be used as novel adaptive biomaterials. We designed and synthesized a range of sugar-containing dynamic proteoid biodynamers based on the polycondensation of different types of amino acid and dipeptide hydrazides with a biological aliphatic dialdehyde and a nonbiological aromatic dialdehyde. By using the saccharide-based dialdehyde, the biocompatibility of biodynamers should be enhanced compared to previously reported biodynamers.

Original languageEnglish
Pages (from-to)16162-16166
Number of pages5
JournalChemistry
Volume23
Issue number64
DOIs
Publication statusPublished - 16-Nov-2017

Keywords

  • Journal Article
  • MOLECULES
  • SEQUENCE
  • COVALENT CHEMISTRY
  • POLYMERS
  • ANALOGS
  • GLYCODYNAMERS
  • OLIGOSACCHARIDES
  • GENERATION

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